BACKGROUND Von Willebrand's disease (VWD) is a common inherited bleeding disorder caused by quantitative deficiency (Type-1 & Type-3 VWD) or qualitative defect of Von Willebrand's Factor (Type-2 VWD). Regarding VWD limited studies are available in Pakistan. The current study was aimed to determine the clinical presentation and frequency of types of VWD. METHODS A cross sectional study was car...

OBJECTIVE The objectives of this study were to determine the relation between maternal education and various maternal risk factors, identify the impact of maternal education on the risk of childhood handicap and estimate the proportion of childhood handicap that can be prevented by maternal education. METHODS Data was collected from all married women attending the two major maternity and chil...

BACKGROUND Rahim Yar Khan (RYK) District is a multi-ethnic assemblage of both ancient and migrated communities in Southern Punjab, Pakistan. There is a paucity of knowledge on the bio-demographic structure of this endogamous population. METHODS We have carried out a cross-sectional epidemiological study in RYK District and recruited 2174 random Muslim married females. Detailed account of mari...

OBJECTIVE To determine the frequency and clinical features of bleeding disorders in the tribe as a result of consanguineous marriages. DESIGN Cross Sectional Study INTRODUCTION Countries in which consanguinity is a normal practice, these rare autosomal recessive disorders run in close families and tribes. Here we describe a family, living in village Ali Murad Chandio, District Badin, labele...

There have been a number of previous estimates of human inbreeding for Britons of British descent in Britain, each generally for different social classes, geographical regions, and/or time periods. In this study I attempted to collect all relevant published studies and combine these disparate results into an integrated whole for all of Britain. This was achieved by combining weighted means of t...

BACKGROUND It seems that there is a relationship between consanguinity and profound hearing loss but there is little data about the association of consanguinity and hearing loss in Iran. OBJECTIVES The aim of this study is to demonstrate the causes of profound bilateral sensorineural hearing loss among Iranian samples who are candidates for cochlear implantation. METHODS This study was retr...

There have been a number of previous estimates human inbreeding for Britons British descent in Britain, each generally different social classes, geographical regions, and/or time periods. In this study I attempted to collect all relevant published studies and combine these disparate results into an integrated whole Britain. This was achieved by combining weighted means the percentage consanguin...

During the early years of Christianity there were major social and legal differences in attitude towards consanguineous marriage in the Eastern and Western Roman empires, reflecting pre-existing divisions between the Classical Greek and Roman worlds. In Athens and Sparta first-cousin, uncle–niece and half-sib marriages were permissible, with half-sib marriage, and even full-sib marriage continu...

Aim: In this article, we aimed to contribute the outcomes of consanguineous marriage literature by analyzing fetal results in population.
 Material and Method: We included 185 patients retrospective research. Demographic, clinical, ultrasonographic delivery data were received from electronic patient records. Also, recorded postnatal results, findings infants. By combining all data, reporte...