Aiming towards a sustainable supply chain, Physical Internet (PI) has been presented as global logistics network with standardized PI-containers. PI-nodes, and more specifically PI-hubs, are one of the key elements concept. This paper focuses on optimising operations in Road-Road PI-hub, which was not addressed literature. PI-hubs designed to transfer PI-containers between suppliers’ customers’...

Protein receptor conformations, obtained from molecular dynamics (MD) simulations, have become a promising treatment of its explicit flexibility in molecular docking experiments applied to drug discovery and development. However, incorporating the entire ensemble of MD conformations in docking experiments to screen large candidate compound libraries is currently an unfeasible task. Clustering a...