The structurally related MAPK-activated protein kinases (MAPKAPKs or MKs) MK2, MK3 and MK5 are involved in multiple cellular functions, including cell-cycle control and cellular differentiation. Here, we show that after deregulation of cell-cycle progression, haematopoietic stem cells (HSCs) in MK2-deficient mice are reduced in number and show an impaired ability for competitive repopulation in...

Most dendritic cell (DC) responses to Toll-like receptor (TLR) ligands depend on the activation of mitogen-activated protein kinases (MAPKs), but the contributions of the many MAPK-activated kinases (MKs) that act ‘downstream’ of the MAPKs Erk and p38 are not known. Here we sought to determine which MKs are required for acute TLR-driven, MAPK-dependent DC endocytic responses. Two specific and s...

An XRF analyser suitable for measuring up to 15 liters of slurry has been tested in the laboratory. A range of slurries consisting of approximately 40 wt% solids and low concentrations of tantalum were obtained and measured. The accuracy of the analyser has been determined to be ±2 ppm (1 sigma). Improvements are planned that will significantly increase the speed and accuracy of the analyser an...

By the time of submission deadline, we completed two tasks: known-item search and discussion search. For both tasks, we used the PADRE retrieval system [1], in which the Okapi BM25 relevance function was implemented. Each message in the collection was treated as an independent document, so both topic distillation scoring and same site suppression mechanism were turned off (i.e. -nocool and –SSS...

Frank Reith, Maggy F Lengke, Donna Falconer, David Craw and Gordon Southam School of Earth and Environmental Sciences, The University of Adelaide, CSIRO Land and Water, Waite Laboratories, Urrbrae, South Australia, Australia; Geomega Inc., Boulder, CO, USA; Department of Geology, University of Otago, Dunedin, New Zealand and Department of Earth Sciences, The University of Western Ontario, Londo...

P. Raniga, K. Pannek, J. Fripp, D. Raffelt, P. Bourgeat, O. Acosta, D. Tournier, A. Connelly, S. Rose, and O. Salvado CSIRO Preventative Health National Research Flagship ICTC, The Australian e-Health Research Centre, Brisbane, Queensland, Australia, Centre for Magnetic Resonance, University of Queensland, Brisbane, Queensland, Australia, UQ Centre for Clinical Research, University of Queenslan...

RICHARD SCHODDE, J. V. REMSEN, JR. , ERIN E. SCHIRTZINGER, LEO JOSEPH & TIMOTHY F. WRIGHT Australian National Wildlife Collection, CSIRO Ecosystem Sciences, GPO Box 1700, Canberra, ACT 2601, Australia Museum of Natural Science & Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, USA. E-mail: [email protected] Department of Biology, New Mexico State Univer...

1 Oceans and Atmosphere (CSIRO), Hobart, TAS, Australia, 2 Tasmanian School of Business and Economics, University of Tasmania, Hobart, TAS, Australia, 3 Centre for Marine Socioecology, University of Tasmania, Hobart, TAS, Australia, 4 Faculty of Agriculture, University of Pattimura, Ambon, Indonesia, 5 Indonesia Project, Arndt-Corden Department of Economics, Crawford School of Public Policy, Au...

Mass balance inverse modelling of methane in the 1990s using a Chemistry Transport Model T. M. Butler , I. Simmonds, and P. J. Rayner School of Earth Sciences, Melbourne University, Australia CSIRO Atmospheric Research, Melbourne, Australia Present affiliation: Max Planck Institute for Chemistry, Mainz, Germany Received: 7 April 2004 – Accepted: 24 May 2004 – Published: 22 June 2004 Corresponde...