Aberrations in cutaneous T-cell immunology may result in rashes that recur at the same or similar sites in the skin, and include fixed drug eruption, psoriasis and mycosis fungoides (MF). Here we describe a patient with an unusual presentation of a cutaneous CD30 + lymphoproliferative disorder, manifesting as a rash with a tendency to repeatedly appear at the same skin locations before spontane...

• Un diagnostic précoce de l’eczéma herpeticum et une thérapie antivirale systémique immédiate peuvent minimiser les complications graves et mortelles. Eczema herpeticum, also known as a form of Kaposi varicelliform eruption caused by viral infection, usually with the herpes simplex virus (HSV), is an extensive cutaneous vesicular eruption that arises from pre-existing skin disease, usually ato...

Fixed drug eruption (FDE) is a cutaneous adverse drug eruption characterized by skin lesions which recur in the same sites upon reexposure to the drug.1,2 It may occur as single or multiple lesions affecting any part of the body, with predilection for the genitalia, hands and lips.1 Loxoprofen sodium hydrate3 (LX-P) (Loxonin; Daiichi Sankyo Co., Ltd, Tokyo, Japan) is a nonsteroidal antiinflamma...

© 2010 The Authors. doi: 10.2340/00015555-0754 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Lichenoid drug eruption (LDE) following furosemide intake has been reported once in the literature (1). Several cases of bullous eruption (2) and generalized exanthematic pustulosis (3) caused by this drug have also been describ ed. We report here the case of a patient who d...

In Rheumatology there are several diseases that frequently develop cutaneous manifestations creating diagnostic difficulties. The Sweet's syndrome appears as archetype of the neutrophilic dermatosis,which is a group of not infectious illnesses, characterized for a dermic neutrophilic and angiocentric infiltrated. The four main features that define this syndrome are: cutaneous eruption, fever, p...

Lichenoid drug eruption is a rare side effect which may occur following administration of several types medication. The pathogenesis lichenoid postulated to be due persistent activation CD8 T lymphocytes against epidermal cells. There were only few cases Amlodipine-induced reported in literature. Due the occurrence, this disease might overlooked and lead delayed diagnosis treatment. It vital fo...

Background. Generalized fixed drug eruption is a specific variant of fixed drug eruption with multifocal lesions. Diagnosis of this drug reaction is straightforward, but occasionally recognition of the causative drug is not possible. This study was aimed at evaluating the clinical features and culprit drugs in generalized fixed drug eruptions in the west of Iran. Method. This cross-sectional st...

Cutaneous immune-related adverse events (cirAEs) are the most prevalent complication to arise from immunotherapy. We determined spectrum, timing, clinical features, and outcomes of cirAEs by conducting an observational pharmacovigilance study (ClinicalTrials.gov, NCT04898751) employing Vigibase, WHO’s global database individual case safety reports. Using a Bayesian confidence propagation neural...

BACKGROUND Unlike T-cell neoplasms, B-cell lymphoproliferative disorders have a limited clinical spectrum of skin involvement. Cutaneous B-cell neoplasms mimicking rosacea or rhinophyma are rare. OBSERVATIONS We described 12 patients with B-cell lymphoproliferative neoplasms presenting with a facial eruption clinically mimicking rosacea or rhinophyma. Eleven patients were women; ages ranged f...