background: sex steroids and their receptors exist in hippocampus and affect spatial learning and memory. this study was designed to measure testosterone level of ca1 and to assess the effect of spatial learning on its amount in left and right hippocampus of adult male rats. methods: sixteen rats were divided into two intact and castrated groups, and then trained in morris water maze (mwm). ano...

a person, who is talented, performs in a certain capacity above the norm. talent is different from intelligence which is a response to a circumstance using knowledge and skill. the attributes of talent are exceptional memory, rapid processing speed, and high motivation, an affinity for learning, creativity and optimal cognition. there is some proof suggests that certain aspects of talent are re...

introduction: gap junctions are intercellular membrane channels that provide direct cytoplasmic continuity between adjacent cells. this communication can be affected by changes in expression of gap junctional subunits called connexins (cx). changes in the expression and function of connexins are associated with number of brain neurodegenerative diseases. neuroinflammation is a hallmark of vario...

Multiple sclerosis (MS) is an autoimmune mediated neurodegenerative disease characterized by demyelination and oligodendrocyte (OL) loss in the central nervous system and accompanied by local inflammation and infiltration of peripheral immune cells. Although many risk factors and symptoms have been identified in MS, the pathology is complicated and the cause remains unknown. It is also unclear ...

Nerve conduction studies are an essential part of the work-up of peripheral neuropathies. Many neuropathic syndromes can be suspected on clinical grounds, but optimal use of nerve conduction study techniques (in combination with needle electromyography) allows diagnostic classification and is therefore crucial to understanding and separation of neuropathies. Multifocal motor neuropathy, for exa...

OBJECTIVE To determine non-invasively the relation between the degree of axonal loss and the extent of demyelination in chronic lesions visible on MRI in patients with different subgroups of clinically definite multiple sclerosis using (1)H magnetic resonance spectroscopy ((1)H MRS) and magnetisation transfer imaging (MT). Conventional MRI is unable to differentiate between the various patholog...