The developmental neurotoxicity of organophosphates involves mechanisms other than their shared property as cholinesterase inhibitors, among which are excitotoxicity and oxidative stress. We used PC12 cells as a neurodevelopmental model to compare the effects of chlorpyrifos and diazinon on the expression of genes encoding glutamate transporters. Chlorpyrifos had a greater effect in cells under...

Objective: Diazinon causes oxidative stress and dysfunction of the liver. This study was undertaken to evaluate the effects of the hydroalcoholic extract of Terminalia chebula, on some biochemical and histopathological parameters of liver tissue in diazinon-administered rats. Materials and Methods: Wistar rats were orally administered with 25 mg/kg body weight diazinon. Vehicle (distilled water...

For the organophosphate pesticide chlorpyrifos, median inhalation noncancer, acute children's exposures in agricultural communities are elevated above reference doses; for diazinon, similar exposures are nearly elevated. We used multivariate linear regression analysis to examine the temporal and spatial associations between agricultural use and measured air concentrations of chlorpyrifos, chlor...

Organophosphate pesticides are widely used and recent studies suggest associations of in utero exposures with adverse birth outcomes and neurodevelopment. Few studies have characterized organophosphate pesticides in human plasma or established how these levels correlate to urinary measurements. We measured organophosphate pesticide metabolites in maternal urine and chlorpyrifos and diazinon in ...

The pesticide diazinon was determined in its insecticidal formulations by square wave adsorptive stripping voltammetry. The method of its determination is based on the irreversible reduction reaction at the hanging mercury drop electrode. The optimal signal was detected at -1.05 V vs. Ag/AgCl in Britton-Robinson buffer at pH 4.4. Various parameters such as pH, buffer concentration, frequency, a...

Rainfall samples were collected during the 2003 and 2004 growing seasons at four agricultural locales across the USA in Maryland, Indiana, Nebraska, and California. The samples were analyzed for 21 insecticides, 18 herbicides, three fungicides, and 40 pesticide degradates. Data from all sites combined show that 7 of the 10 most frequently detected pesticides were herbicides, with atrazine (70%)...

Objective Diazinon is an organophosphate pesticide and today this pesticide is mostly used in agriculture. In this study, we analyzed the effects of diazinon and vitamin E on apoptosis and the proliferation of germ cells in rat testis. MaterialsAndMethods In this experimental study 30 male wistar rats, were divided into five groups (N=6). Control, sham (received olive oil), experimental group 1...

The study was undertaken to determine the purity level of eleven selected pesticides collected from different locations Bangladesh. In this study, Gas Chromatography coupled with Flame Ionization Detector (FID) and Electron Captured (ECD) used acephate, diazinon, dimethoate, chlorpyrifos, quinalphos, malathion, fenitrothion cypermethrin, fenvalerate. High Performance Liquid (HPLC 20A Prominence...