BACKGROUND The World Health Organization refers to stroke, the second most frequent cause of death in the world, in terms of pandemic. Present treatments are only effective within precise time windows. Only 10% of thrombolysis patients are eligible. Late assessment of the patient resulting from admission and lack of knowledge of the symptoms is the main explanation of lack of eligibility. MET...

BACKGROUND Skilled attendance at childbirth is crucial for decreasing maternal and neonatal mortality, yet many women in low- and middle-income countries deliver outside of health facilities, without skilled help. The main conceptual framework in this field implicitly looks at home births with complications. We expand this to include "preventive" facility delivery for uncomplicated childbirth, ...

The relevance. Access to digital content is becoming increasingly important in today’s world, and libraries play an essential role providing such access a wide range of users, including the ones with disabilities. However, despite efforts many ensure accessibility, still fall short equal all users. This problem highlights relevance conducting assessments accessibility library websites, order id...

Abstract Since the mid-20th century, assessing performance of built environment was recognized as an instrument to improve efficiency in design and construction processes. However, it appears difficult identify assessment tools that currently include a holistic inclusion, diversity, equity accessibility criteria for environments. A systematic literature review performed define state art domain ...

INTRODUCTION AND OBJECTIVES To evaluate the readability, accessibility, usability, and reliability of information available on the Internet in the Spanish language about aortic aneurysm and its endovascular treatment, and to determine whether this information source provides comprehensible material that will enable patients to participate in decisions regarding their condition. METHODS In Nov...

Evolutionary pathways describe trajectories of biological evolution in the space of different variants of organisms (genotypes). The probability of existence and the number of evolutionary pathways that lead from a given genotype to a better-adapted genotype are important measures of accessibility of local fitness optima and the reproducibility of evolution. Both quantities have been studied in...

Most patients with asthma are easily diagnosed and respond to standard treatment with a short-acting inhaled β2agonist for symptom control and long-term treatment with an inhaled corticosteroid in doses of up to 2,000 μg daily. Approximately 5% of patients do not respond to this regime and require further investigation to establish the reasons for the lack of response. "Difficult asthma" may be...