a serum phosphorus if ATPase enzyme is available. Maintenance plasma levels range between 10 and 40 m,ug/ml with a mean value of 25 mrjug/ml. There is overlapping of maintenance and toxic serum levels in the higher ranges. Values over 45 m,ug/ml warrant careful evaluation for digitalis intoxication. Maintenance plasma levels can be achieved with or without the usual digitalizing dosage if time ...

For many years it has been suggested that considerable quantities of digitalis bodies accumulate in edema fluid, that rapid diuresis with mercurial diuretic drugs "liberates" these glycosides into the blood stream as the edema fluids are mobilized and excreted by the kidneys, and that the ensuing "redigitalization" may lead to manifestations of digitalis toxicity in the already adequately digit...

The binding of verapamil to the protein human serum albumin (HSA) was examined by using high-performance affinity chromatography. Many previous reports have investigated the binding of verapamil with HSA, but the exact strength and nature of this interaction (e.g. the number and location of binding sites) is still unclear. In this study, frontal analysis indicated that at least one major bindin...