A molecular manipulation efforts were made at β carbon of α, β unsaturated site of nalidixic acid by Michael addition, in expectation to get newer chemimanipulated derivatives with potent/modified antimicrobial spectrum. At the ends of chemimanipulative work, totally 5 derivatives were synthesized and characterized by spectral data. All the derivatives were screened for its antibacterial activi...

Background and objectives: Resistance towards reveling antibiotics has captured great interest in evaluating the antimicrobial properties of the natural plants. Taraxacum mongolicum is widely used as a folklore medicinal plant for its diuretic, antirheumatic and anti-inflammatory properties. Though there are some reports on antimicrobial properties of Taraxacum mongolicum, studies on antibacter...

Dental caries was the most common disease in both adults and children. Streptococcus mutans is main bacteria causing plaque formation initiator of dental caries. Antibacterials derived from plants can be used to prevent formation. Taro (Colosia esculenta) has been traditional medicine. Antibacterial compounds have discovered C. esculenta leaves. This study aimed determine ability leaf ethanol e...

background : the aim of this study was to determine the antibacterial activity of zataria multiflora boiss (avishan-e shirazi) and carum copticum (zenian) extracts on vibrio cholerae american type culture collection (atcc14035)and v. cholerae persian type culture collection (ptcc1611) strains. methods : antimicrobial effects of the extracts were assayed by disc diffusion and broth microdilution...

Fresh flowers of Tagetes erecta L., the flavonoid was isolated by extraction and fractionation with different solvents. It was then identified as patulitrin (10mg/100ml) by various tests. It was then subjected to disc diffusion assay to assess its antibacterial potentials against Alcaligens faecalis, Bacillus cereus, Campylobacter coli, Escherchia coli, Klebsiella pneumoniae, Pseudomonas aerugi...

The aim of this study was to characterize the phytochemicals and investigate antimicrobial efficacy shade dried roots Asparagus adscendens. powder were extracted with chloroform after removal solvent under reduced pressure subjected for chromatographic separation. After column chromatography purification five compounds i.e .hexacosanyltriacontanoate, hexatriacontanone, 2,3,5,7-tetramethoxydi hy...

Plant oils and oil components were screened in vitro for antibacterial and antifungal activity by disc diffusion method. Minimum Inhibitory Concentrations (MICs) of oils (% v/v) against bacteria and fungi were determined by agar dilution method. Results showed that potential antimicrobial activity was demonstrated by geranium oil, geraniol, and terpineol. These oils and oil components were acti...

In different folk medicine Ziziphus spina-christi is used for different purposes such as pneumonia, dysentery, scorpion stings, cough, constipation, intestinal worms and fever. The aim of this study was evaluation and comparing the antibacterial activity of methanolic and ethanolic extracts of Ziziphus spina –christi as well as subsequent structural changes in affected bacteria. For this purpos...

BACKGROUND Anethum graveolens Linn., Foeniculum vulgare Mill. and Trachyspermum ammi L. are widely used traditional medicinal plants to treat various ailments. To provide a scientific basis to traditional uses of these plants, their aqueous and organic seed extracts, as well as isolated phytoconstituents were evaluated for their antibacterial potential. METHODS Antibacterial activity of aqueo...