BACKGROUND Tuberculosis (TB) accounts of much of the morbidity and mortality associated with HIV. We evaluate the cost-effectiveness of different strategies to actively screen for TB disease in HIV positive individuals, where isoniazid preventative therapy (IPT) is given to those screening negative, and use value of information analysis (VOI) to identify future research priorities. METHODOLOG...

increased services, increased attention to unmet needs, and greater cost-effectiveness. Studies in Guatemala and Mexico showed that client screening resulted in greater information given to clients as well as important improvements in the use of services (Vernon and Foreit 1999). In a study in Peru, the screening intervention increased the number of services provided per client visit by 13 perc...

background: the objective of this study is to estimate the average diagnosis and treatment costs of chronic hepatitis b and c, with respect to different therapeutic strategies in iran. methods: this is a descriptive, analytical, and cross‑sectional study carried out on patients with hepatitis b and c, who were referred to the liver disease research center for prevention and treatment of hepatit...

OBJECTIVE A vaccine for Lyme disease was approved in 1998 for use in the US. Given the high cost of the vaccine, the low risk of Lyme disease in many areas, and the largely curable nature of the disease, the cost-effectiveness of the vaccine in various risk groups is uncertain. This study was undertaken to examine the cost-effectiveness of the Lyme disease vaccine and the factors that influence...

BACKGROUND Studies of cost-effective disease prevention have typically focused on the tradeoff between the cost of disease transmission and the cost of applying control measures. We present a novel approach that also accounts for the cost of social disruptions resulting from the spread of disease. These disruptions, which we call social response, can include heightened anxiety, strain on health...