background: non-communicable diseases (ncds) annually kill over 35 million people worldwide. they are responsible for nearly two-thirds of the world's deaths. global health is facing a dramatic change. for the first time in human history, more than 80% of ncd-related deaths are in low- and middle-income countries. countries throughout the world are expected to lose significant amounts of nation...

introduction: in recent years, a few studies have been conducted in the area of the cost-effectiveness of the eplerenone; it's notable that coherent and clear evidence are not available. therefore, this study aimed to systematically review studies of cost-effectiveness of eplerenone in the treatment of cardio-vascular patients. methods: this systematic review study was conducted in 2016. t...

background glucose-6-phosphate dehydrogenase (g6pd) enzyme deficiency is one of the prevalent disorders in guilan province, northern iran, causing many patients to suffer from acute hemolysis. this disease has imposed tremendous costs both on patients and health systems. the aim of this study was to compare the direct costs of favism treatment on patients and health system with g6pd enzyme scre...

background hepatitis b infection is still the main cause of chronic liver disease in iran, which is associated with significant economic and social costs. objectives this study aimed to estimate the financial burden caused by chb infection and its complications in iran. results the total annual cost for the activate population of chb patients and for those receiving treatment at various disease...

conclusions the results confirmed that the total costs for non-alcoholic fatty liver among the iranian adult urban population alone exceeded 1 billion ppp$ per year. these costs can be saved or reduced by effective disease management and early prevention. objectives this study aims to estimate the diagnosis and treatment costs of non-alcoholic fatty liver. patients and methods this cross-sectio...

background: myocardial infarction (mi) occurs due to heart muscle death that costs like human life, which is higher than the treatment costs. this study aimed to present an mi prediction model using classification data mining methods, which consider the imbalance nature of the problem. methods: we enrolled 455 healthy and 295 myocardial infarction cases of visitors to shahid madani specialized ...

background: multiple sclerosis is a common and chronic neurologic disorder. this disorder imposes physical, economic, and psychosocial burden on individuals, their families and society. this study aims to analyze the costs of multiple sclerosis disease based on the severity of disability. methods: we performed a cross‑sectional cost of illness study. this study was conducted in 332 patients of ...

background: disease-modifying drugs (dmds) are a significant expenditure for treating multiple sclerosis (ms). however, there is limited report on assessment of the cost-utility of dmds compared with symptom management in the presence of long-term data. this study aimed to assess the lifetime cost-utility from the iranian healthcare perspectives of 4dmds relative to symptom management alone in ...