Speculative evaluation can improve the performance of parallel graph reduction systems through increased parallelism. Although speculation is costly, much of the burden can be absorbed by processors which would otherwise be idle. Despite the overhead required for speculative task management, our prototype implementation achieves 70% eeciency for speculative graph reduction, with little impact o...

Speculative multithreading holds the potential to substantially improve the execution performance of sequential programs by leveraging the resources of multiple execution contexts (e.g., processors or threads). For unstructured non-numeric programs, the three key challenges of parallelization are (1) predicting the sequence of tasks (i.e., groups of instructions) that corresponds to the correct...

This paper introduces a router delay model that accurately models key aspects of modern routers. The model accounts for the pipelined nature of contemporary routers, the specific flow control method employed, the delay of the flowcontrol credit path, and the sharing of crossbar ports across virtual channels. Motivated by this model, we introduce a microarchitecture for a speculative virtual-cha...

Abstract Background and Objectives Clinical features of SARS-COV-2 virus include fever, headache, cough, sore throat, and shortness of breath, and in severe forms it leads to disseminated intravascular coagulation, septic shock, and ultimately death. Excessive secretion of proinflammatory cytokines such as TNF-α, IL-6, and IL-1 leads to cytokine storms in this disease. The emergence of new va...

We appreciate the perspective provided by Dr. Culp in describing the acceptance by scientists of the highly regulated environment for classified physics research (1). We agree that as more microbiology research falls into the category of “dual-use research of concern” or DURC, it is important to consider the experience in fields such as physics, whose members had to learn how to deal and work w...