Research to understand variability at the highest end of the cognitive performance distribution has been scarce. Our aim was to define a cognitive endophenotype based on exceptional episodic memory (EM) performance and to investigate familial aggregation of EM in families from the Long Life Family Study (LLFS). Using a sample of 1911 nondemented offspring of long-lived probands, we created a qu...

Erythromycin (EM), a macrolide antibiotic has been recently reported to depress the extent of inflammation irrespective of its antimicrobial action. Our study was initiated to examine the effect of EM on T cell proliferation in vitro, since other macrolide antibiotics FK506 and rapamycin (RAP) have been well known to possess strong immunosuppressive or anti-inflammatory potential. EM had a supp...

Em um estudo recente conduzido por Stourac et al., discutiu-se se rocurônio e sugamadex beneficiam o tempo para intubação traqueal e outros desfechos do bloqueio neuromuscular (BNM) em comparação com succinilcolina, rocurônio e neostigmina em mulheres submetidas à anestesia geral para cesariana.1 A conclusão dos autores foi que rocurônio usado para indução de sequência rápida não é inferior em ...

in this paper, we consider the fuzzy fixed-charge transportation problem (ffctp). both of fixed and transportation cost are fuzzy numbers. contrary to previous works, electromagnetism-like algorithms (em) is firstly proposed in this research area to solve the problem. three types of em; original em, revised em, and hybrid em are firstly employed for the given problem. the latter is being firstl...

Los Angeles and Orange Counties are known endemic areas for murine typhus in California; however, no recent reports of flea-borne rickettsioses are known from adjacent San Bernardino County. Sixty-five opossums (Didelphis virginiana) were trapped in the suburban residential and industrial zones of the southwestern part of San Bernardino County in 2007. Sixty out of 65 opossums were infested wit...

OBJECTIVE To evaluate how continuation of and alterations to initial year 1 combination etanercept-methotrexate (MTX) therapy and MTX monotherapy regimens affect long-term remission and radiographic progression in early, active rheumatoid arthritis. METHODS Subjects were randomized at baseline for the entire 2-year period; those who completed 1 year of treatment with combination or MTX monoth...

Usando um espectrômetro baseado em um SQUID (dispositivo supercondutor de interferência quântica), de alta temperatura de transição, polarizado continuamente, medimos sinais de ressonância magnética nuclear (RMN) de várias amostras a temperatura ambiente em campos magnéticos na faixa entre 0,05 mT e 2 mT. É possível observar sinais de prótons em uma amostra com 1 mL de óleo mineral em 2 mT com ...

Bayesian networks (BN) are used in a big range of applications but they have one issue concerning parameter learning. In real application, training data are always incomplete or some nodes are hidden. To deal with this problem many learning parameter algorithms are suggested foreground EM, Gibbs sampling and RBE algorithms. In order to limit the search space and escape from local maxima produce...