a physic-mathematical model has been developed that is suitable for biosensors incorporating membranes and bisubstrate enzymes. the set of equations regarding the transport of reactants across the membrane, the bisubstrate enzymatic reaction, back diffusion of reactants and reaction products, are written down and simultaneously solved and transient response of the electrode is determined as a f...

Objective(s): Alginates play a key role in mucoid Pseudomonas aeruginosa colonization, biofilm formation, and driving out of cationic antibiotics. P. aeruginosa alginate lyase (AlgL) is a periplasmic enzyme that is necessary for alginate synthesis and secretion. It also has a role in depolymerization of alginates. Using AlgLs in cystic fibrosis patients along with anti...

       Osteoporosis is a disease of high prevalence with increased bone loss. It has potential public health threat and that the health authorities had taken several measures for its control. In recent years, considerable attention has been given to physiopathology of osteoporosis. Oxidative stress has been proved to be involved in bone resorption. Oxidative stress occurs when balance between o...

The number of patients with end-stage renal disease is growing rapidly in Asia. Patients with end stage renal disease failure (ESRD) undergoing long term hemodialysis (HD) are at risk for high oxidative stress. There is paucity of information with regard to oxidative stress during HD. Therefore, the aim of the present study was to evaluate catalase enzyme activity in erythrocytes and the total ...

Phenoloxidase (Po) activity was measusred spectrophotometrically in serum, plasma and haemocytes (HLS) of the freshwater crayfish (Pontastacus leptodactylus). The highest activity was found in HLS suggesting that the haemocytes are the major source of the Po or its proform prophenoloxidase (proPO) in crayfish. Furthermore, the enzyme activity in serum samples was reduced after freezing the samp...

Diabetes mellitus is a metabolic disorder characterized by chronic hyperglycemia. The management of the blood glucose level is a critical strategy in the control of diabetes complications. Inhibitors of carbohydrate hydrolyzing enzymes have been useful as oral hypoglycemic drugs for the control of hyperglycemia especially in patients with type II disables mellitus. The goal of the present study...

conclusions the results indicated that sod-loaded in sln was delivered into deep burned skin layer and induced high enzyme activity through the skin. low particle size, application of lecithin as surfactant and low crystallinity index (ci) percentage were important factors for increasing sod penetration through the burned rat skin. percentage of activity by sln dispersions through rat skin was ...

hydatidosis is a zoonosis disease caused by the larva of echinococcus granulosus parasite in man and animals. the proteases enzymes are necessary for nutrition, migration and evasion of immunity of parasite into host. the aim of this study was to determine the protease activity of hydatid cyst protoscolices (psc), healthy and cystic liver tissues in order to compare of this biomarker for host a...