Strategies to increase expanded criteria donor (ECD) transplantation are needed. We quantified the extent to which ECD kidneys provide recipients with a lifetime of allograft function by determining the difference between patient survival and death-censored allograft survival (graft survival). Initial analyses compared 5-year outcomes in the Eurotransplant Senior Program (European) and the Unit...

L1 is a cell adhesion molecule of the immunoglobulin (Ig) superfamily, critical for central nervous system development, and involved in several neuronal biological events. It is a type I membrane glycoprotein. The L1 ectodomain, composed of six Ig-like and five fibronectin (Fn) type-III domains, is involved in homophilic binding. Here, co-immunoprecipitation studies between recombinant truncate...

OBJECTIVE First, to determine the distribution of the estimated sources of sleep spindles, and alpha and mu rhythms based on whole-head magnetoencephalogram (MEG) recordings; second, to scrutinize the physiological relevance of the dipole fit algorithm in localizing on-going normal rhythmic activities. METHODS One hundred and fifty-one channels were used to record spontaneous MEG activity dur...

E-cadherin, a member of the cadherin family, plays a major role in cell-cell adhesion of normal epithelium. Recent studies have shown that reduction or loss of E-cadherin expression in carcinomas have some relationship with their clinicopathological manifestation including invasion and metastasis. In the present study, we have established cell clones with different E-cadherin expression from hu...

The recording radius and spatial selectivity of an extracellular probe are important for interpreting neurophysiological recordings but are rarely measured. Moreover, an analysis of the recording biophysics of multisite probes (e.g., tetrodes) can provide for source characterization and localization of spiking single units, but this capability has remained largely unexploited. Here we address b...

We use Zooglider, a low-power optical zooplankton-sensing glider, to test the covariability of fine-scale vertical distributions six omnivorous zooplankton taxa with three different representations their potential prey field: small suspended particles (equivalent circular diameter [ECD] between 0.25 and 0.45 mm), marine snow (ECD ≥ chlorophyll (Chl a), in San Diego Trough. All fields tend be hi...

Early Childhood Development (ECD) has become a priority area of social work, in both developed and developing countries. In this article, the term ECD supervisors refers to workers working with centres capacity supervisor. These can provide valuable insight into unique management tasks associated professional development areas uniquely required when sector. The goal conceptual article is identi...

Previous results in cylindrical volumes have shown that action potentials generate far-field potentials when experimental conditions are such that quadrupolar components of the action potential are reduced to an equivalent dipole. We now show that the same conclusions are also reached within a spherical volume, again recording far-field potentials from isolated bullfrog nerves. A mathematical p...

Adult humans were unilaterally trained in a tactile discrimination task of sequentially applied multi-finger stimuli. Magnetic source imaging (MSI) was performed before and after the training to evaluate use-dependent neuronal plasticity. All subjects showed fast improvements in performance and complete transfer of the learned task. MSI recordings revealed an unilateral decrease in current dipo...