نتایج جستجو برای: esophageal adenocarcinoma

تعداد نتایج: 104941  

2000
Rhonda F. Souza Kenneth Shewmake David G. Beer Byron Cryer Stuart Jon Spechler Harold C. Simmons

Adenocarcinoma in Barrett’s esophagus has been increasing in incidence at a rapid rate for more than two decades. Cyclooxygenase (COX)-2 appears to play an important role in gastrointestinal carcinogenesis, and COX-2 overexpression has been demonstrated both in esophageal adenocarcinomas and in the metaplastic epithelium of Barrett’s esophagus. The aim of our study was to determine whether sele...

Journal: :Archives of Iranian medicine 2008
Ali-Akbar Haghdoost Hamed Hosseini Goli Chamani Mohammad-Reza Zarei Maryam Rad Maryam Hashemipoor Mohammad-Javad Zahedi Sodif Darvish-Moghadam

BACKGROUND The fall in the incidence of esophageal squamous cell cancer and noncardia gastric cancers in western countries parallels a concomitant rise in the incidence of gastric cardia cancer and distal adenocarcinoma of the esophagus. We aimed to investigate the incidence trend of different gastric and esophageal cancers in Kerman, southeast Iran. METHODS The information of all newly diagn...

2012
Matthias C Schauer Nikolas H Stoecklein Joerg Theisen Feride Kröpil Stephan Baldus Arnulf Hoelscher Markus Feith Edwin Bölke Christiane Matuschek Wilfried Budach Wolfram Trudo Knoefel

BACKGROUND In intestinal epithelium, tyrosine kinase receptor Ephrin B3 (Eph B3) maintains the architecture of the crypt-villus axis by repulsive interaction with its ligand ephrin-B1. While loss of Eph B3 is linked to colorectal cancer initiation, overexpression of Eph B3 in cancer cell lines inhibits growth and induces functional changes with decreased mesenchymal and increased epithelial mar...

2004
John T. Chang

T he incidence of esophageal adenocarcinoma has been rising rapidly over the past few decades. The major risk factors predisposing to the development of adenocarcinoma are long-standing gastroesophageal reflux disease and Barrett esophagus, but other factors may be involved as cancer can occur in their absence. In patients with Barrett esophagus, the extent and degree of dysplasia influence the...

2014
Yasuaki Nagami Hirohisa Machida Masatsugu Shiba Tomoko Obayashi Masaki Ominami Shusei Fukunaga Satoshi Sugimori Hirokazu Yamagami Tetsuya Tanigawa Kenji Watanabe Toshio Watanabe Kazunari Tominaga Yasuhiro Fujiwara Tetsuo Arakawa

BACKGROUND Adenocarcinoma of the esophagogastric junction (EGJ) is uncommon in Eastern countries, including Japan, but it is believed that the incidence of EGJ adenocarcinoma will increase in Asia in the future due to the decreasing incidence of Helicobacter pylori infection. Endoscopic submucosal dissection (ESD) is a minimally invasive and curative treatment that allows precise pathological a...

Background and purpose: Northern Iran has a high incidence for squamous cell carcinoma (SCC) of esophagus, therefore, studying esophageal SCC in different regions of Iran could prepare data for evidence-based and cost effective programs. This study aimed to evaluate esophageal carcinoma in Babol, Northern Iran during 8 years. Materials and methods: This cross-sectional study was conducted in...

2016
Francisco TUSTUMI Cintia Mayumi Sakurai KIMURA Flavio Roberto TAKEDA Rubens Antônio Aissar SALLUM Ulysses RIBEIRO-JUNIOR Ivan CECCONELLO

Background: Knowing esophageal tumors behavior in relationship to lymph node involvement, distant metastases and local tumor invasion is of paramount importance for the best esophageal tumors management. Aim: To describe lymph node involvement, distant metastases, and local tumor invasion in esophageal carcinoma, according to tumor topography and histology. Methods: A total of 444 patien...

Journal: :Therapeutic advances in gastroenterology 2008
Julian A Abrams

The incidence of esophageal adenocarcinoma (EAC) is rising rapidly in Western countries, and effective chemoprevention for this malignancy is lacking. Endoscopic surveillance of patients with Barrett's esophagus is currently employed to diagnose EAC at earlier stages, but this strategy has several limitations. Non-steroidal anti-inflammatory drugs and proton pump inhibitors are the most promisi...

Journal: :Annals of African Surgery 2018

Journal: :Journal of Visceral Surgery 2011

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