The ancestral sequence reconstruction problem asks to predict the DNA or protein sequence of an ancestral species, given the sequences of extant species. Such reconstructions are fundamental to comparative genomics, as they provide information about extant genomes and the process of evolution that gave rise to them. Arguably the best method for ancestral reconstruction is maximum likelihood est...

Over a period of time the volume of network traffic generated by an Internet application is equal to the cumulative size of the packets that carried the traffic. We propose a method of estimating the expected volume of network traffic that will be generated by a population of WorldWide Web users based on estimating the cumulative size of the expected hypertext transfer protocol (HTTP) packets. ...

A new statistical approach for construction of the genetic linkage map and estimation of the parental linkage phase based on allele frequency data from pooled gametic (sperm or egg) samples is introduced. This method can be applied for estimation of recombination fractions (over distances <1 cM) and ordering of large numbers (even hundreds) of closely linked markers. This method should be extre...

This paper describes an empirical study of effort estimation in agile software development. Estimated effort and actual effort of a 46-iteration project are collected and analyzed. The results show that estimation in agile development is more accurate than that in traditional development even though agile developers still underestimate the effort. However, estimation accuracy is not improved ov...

Bayesian semi-parametric estimation has proven effective for quantile estimation in general and specifically in financial Value at Risk forecasting. Expected short-fall is a competing tail risk measure, involving a conditional expectation beyond a quantile, that has recently been semi-parametrically estimated via asymmetric least squares and so-called expectiles. An asymmetric Gaussian density ...

the length-weight relationships for three fish species from beheshtabad river, karun river drainage (western chaharmahal and bakhtiari provinces, iran) were investigated. the values of the slope parameter ( b ) in the length-weight relationship equations were determined as 2.79 for capoeta damascina , 3.10 for chondrostoma regium and 3.09 for oncorhynchus mykiss , all of which were significantl...