Podophyllotoxins represent an important and unique position among natural products. They serve as the starting material for the semi-synthetic anticancer drugs etopside and teniposide, so considerable attention has focused on the availability of these aryltetralin lignans. Linum is one of the genera, with some reports on the presence of podophyllotoxin and related compounds, such as L. album, L...

In recent years, significant progress has been achieved toward increased structured data entry using standardized health care terminologies. Concurrently, the value of narrative as the clinician's rich description of the encounter and source of vital information has been reaffirmed. Natural language processing (NLP) offers a strategy for integrating these approaches to provide structured report...

Species-rich private reserve for sale in Paraguay and other measures, says Environment Minister Manuel Pulgar-Vidal. The measure’s long-term impact may be in doubt, because Peru’s presidential runoff is scheduled for June 5 and the new government will take office July 28, just days after the 60-day emergency period expires. The two candidates, Keiko Fujimori and Pedro Pablo Kuczynski, differ on...

Objective(s): Today, consumers are looking for food products providing health benefits in addition to meeting the basic nutritional needs of the body. This study aimed to evaluate the antioxidant and cytotoxic effects of Liza klunzingeri protein hydrolysate both in vivo and in vitro.Materials and Methods: Fish protein hydrolysate (FPH) w...

Background:Tenofovir is among the first-line treatments for chronic hepatitis B (CHB) virus infection. We evaluated the efficacy of Tenofovir in the treatment of Iranian adult patients with CHB. Methods: In a retrospective study, we evaluated 154 HBsAg positive patients referred to Sadoughi hospital in Yazd-Iran for treatment ...

The Vehicle Routing Problem (VRP) is a well known research line in the optimisation research community. Its different basic variants have been widely explored in the literature. Even though it has been studied for years, the research around it is still very active. The new tendency is mainly focused on applying this study cases to real life problems. Due to this trend, the Rich VRP arises; comb...

The long interspersed repeated DNA family of rats (LINE or L1Rn family) contains about 40,000 6.7-kilobase (kb) long members (1). LINE members may be currently mobile since their presence or absence causes allelic variation at three single copy loci (2, 3): insulin 1, Moloney leukemia virus integration 2 (Mlvi-2) (4), and immunoglobulin heavy chain (Igh). To characterize target sites for LINE i...