PURPOSE The size and organization of stromal collagen fibrils influence the biomechanical and optical properties of the cornea and hence its function. How fibrillar structure varies with position across the cornea has not been fully characterized. The present study was designed to quantify the collagen fibril spacing and diameter across the normal human cornea and to relate this to the properti...

The decellularized cornea has received considerable attention for use as an artificial cornea. The decellularized cornea is free from cellular components and other immunogens, but maintains the integrity of the extracellular matrix. However, the ultrastructure of the decellularized cornea has yet to be demonstrated in detail. We investigated the influence of high hydrostatic pressure (HHP) on t...

PURPOSE To study the phenotypes, distribution, and morphologies of different antigen-presenting cells (APCs) in the murine cornea. METHODS Intravitreal injection of fluorescently tagged ovalbumin (OVA) or antibodies to MHC-II (I-A(d)), F4/80, CD11c, B7-1, and B7-2 was performed to label cells in the murine cornea. Light and transmission electron microscopy were used to examine corneal histolo...

the aim of this study is to map the chronological achievements of public health over the past 100 years in a small island state and to outline emerging themes. a retrospective analysis of data was conducted from the published population and vital statistics reports of the central statistical office for the period of 1953-2006, as well as all available published reports of the ministry of health...

purpose : to compare the outcome of surgery and postoperative complications between using manually dissected cornea in descemet’s stripping with endothelial keratoplasty (dsek) and using eye bank automated precut cornea in descemet’s stripping with automated endothelial keratoplasty (dsaek) methods : forty eyes with indication of endothelial keratoplasty (ek) were included in this randomized pr...

Background & Aims: Amniotic membrane persists for a long time after ocular transplantation (as corneal substitute) and can affect light transmission (transparency). The aim of this study was to evaluate the transparency of amniotic membrane after freeze-drying (lyophilization) and to compare the results with transparency of rabbit cornea. Methods: Transparency of rabbits’ corneas and fresh and ...