there are two different co-expression systems including bicistronic; dual-vector or two-promoter to express two different genes simultaneously and also to study protein-protein interactions. bicistronic system has disadvantages e.g. compared with two-promoter system. in this paper, a simple method based on spliced overlap extension by polymerase chain reaction (soe-pcr) technique was demonstrat...

Cooperative reactivity plays an important role in the oxidation of CO to CO(2) by palladium oxide cations and offers insight into factors which influence catalysis. Comprehensive studies including guided-ion-beam mass spectrometry and theoretical investigations reveal the reaction products and profiles of PdO(2)(+) and PdO(3)(+) with CO through oxygen radical centers and dioxygen complexes boun...

Carbon monoxide (CO), a low-molecular-weight gas, is endogenously produced in the body as a product of heme degradation catalyzed by heme oxygenase (HO) enzymes. As the beneficial roles of HO system have been elucidated in vitro and in vivo, CO itself has also been reported as a potent cytoprotective molecule. Whereas CO represents a toxic inhalation hazard at high concentration, low-dose exoge...

Abstract: The governing equations of motion for a drill string considering coupling between axial, lateral and torsional vibrations are obtained using a Lagrangian approach. The result leads to a set of non-linear equations with time varying coefficients. A fully coupled model for axial, lateral, and torsional vibrations of drill strings is presented. The bit/formation interactions are assumed ...

Statins are most effective pharmacologically agents to decrease total plasma cholesterol level by competitive inhibition of HMG-Co A reductase. Apart from the well-known LDL and cholesterol lowering effect, statins have been postulated to exert other beneficial effects also called pleotropic or non-lipid effects. Better understanding of various pleotropic effects of statins has prompted a new s...

Coordinating Lead Author Paul Ashford (United Kingdom) Lead Authors Andrew Ambrose (Australia), Mike Jeffs (United Kingdom), Bob Johnson (USA), Suzie Kocchi (USA), Simon Lee (United Kingdom), Daniel Nott (USA), Paulo Vodianitskaia (Brazil), Jinhuang Wu (China) Contributing Authors Theresa Maine (USA), John Mutton (Canada), Bert Veenendaal (The Netherlands) Review Editors Jorge Leiva Valenzuela ...

In this paper, surface and piezoelectric effects on the vibration behavior of nanowires (NWs) are investigated by using a Timoshenko beam model. The electric field equations and the governing equations of motion for the piezoelectric NWs are derived with the consideration of surface effects. By the exact solution of the governing equations, an expression for the natural frequencies of NWs with ...