Background and Aim: With the development of industrial maintenance technology, a group pathogens called avian pathogenic Escherichia coli (APEC) became very common. The initiation, development, outcome infectious process mediated by virulent APEC strains occur through decrease in colonization resistance intestine, an immunobiological marker homeostasis stability susceptible species. This study ...

In vitro adherence of Lactobacillus strains to cell and tissue types along the chicken alimentary tract and to ileal mucus were determined. Fresh isolates from chickens adhered to the epithelium of crop and, in a strain-dependent manner, to follicle-associated epithelium and the apical surfaces of mature enterocytes of intestinal villi. No adherence to the apical surfaces of undifferentiated en...

Transcriptional variation in histologically- and genetically- identical cells is a widespread phenomenon in tissues, yet the processes conferring this heterogeneity are not well understood. To identify contributing factors, we analyzed epigenetic profiles associated with the in vivo transcriptional gradient of the mouse lactase gene (Lct), which occurs in enterocytes along the proximal-to-dista...

Quantitative analysis of Yersinia pseudotuberculosis infection of murine gut loops revealed that significantly more wild-type bacteria associated with Peyer's patch M cells than with dome enterocytes or goblet cells. An invasin-deficient mutant was significantly attenuated for M-cell invasion, while beta1 integrin expression was demonstrated in the apical membranes of M cells but not enterocyte...

The uptake and release of chlamydiae in infections of highly specialized intestinal, absorptive epithelial cells of the ileum of newborn calves were studied. Infection occurred only through the brush border of the enterocytes. The chlamydial elementary bodies were adsorbed onto the microvilli, a process that induced pinocytosis of the elementary bodies and formation of endosomes containing one ...

The development of the ferret ileum was studied in order to determine the pattern of morphological maturation during the postnatal period. In the newborn, intestinal villi were short, and lined by simple columnar enterocytes with striated borders and small vacuoles. At one week old, the equivalent cell had large vacuoles that were shown on TEM to be related to a tubulovesicular system in the ap...