Inositol hexakisphosphate kinase 3 (IP6K3) generates inositol pyrophosphates, which regulate diverse cellular functions. However, little is known about its own physiological role. Here, we show the roles of IP6K3 in metabolic regulation. We detected high levels of both mouse and human IP6K3 mRNA in myotubes and muscle tissues. In human myotubes, IP6K3 was upregulated by dexamethasone treatment,...

At percent, Zn stress tolerance using novel genetic resources is an important mitigation strategy for plant breeding. In this study, thirty-five durum wheat genotypes with different growth habits were evaluated under normal (non-stress) and Zn deficient stress during the 2014-15 cropping season. A total of ten Zn stress tolerance indices including stress tolerance index (STI), relative zinc-def...

This study compares salinity tolerance between red and black shell Pinctada fucata stress of 20 50‰, while 35‰ was used as a control. The hemolymph osmotic pressure, inorganic ion concentration, the activities Na + -K -ATPase, respiratory metabolism related enzymes liver tissue antioxidant were measured at 12 24 h after stress. pressure concentration two strains P. increased significantly with ...

OBJECTIVES This study evaluated a simple relaxation breathing exercise for acute improvement of postprandial glycemic and insulinemic status. DESIGN Healthy human subjects were randomized to control breathing (CB; n=13) or a relaxation breathing exercise (RB; n=13) that was repeated every 10 minutes for the 30 minutes before and 90 minutes after consuming a glucose challenge (oral glucose tol...

Hepatic plasma membrane lactate transport was studied in isolated hepatocytes prepared from fed, starved, and streptozotocin diabetic rats. Carrier-mediated lactate entry was determined using the lactate transport inhibitors alpha-cyano-3-hydroxycinnamate and D-3-hydroxybutyrate and was significantly greater in hepatocytes from starved compared to fed rats and in hepatocytes from diabetic fed c...

Background: Toxoplasma gondii is an intracellular protozoan with worldwide distribution capable of infecting all endothermic vertebrates. Latent toxoplasmosis in man and animals is considered as clinically asymptomatic. The aim of this Study is evaluation of the effects of Toxoplasma gondii on Biochemical Parameters of Reproductive Function in Male Rats. Materials and Methods: A total of 56 mal...

in order to increase drought tolerance in bread wheat, an appropriate breeding program based on inheritance of drought tolerance is recommended. in the present study, nine bread wheat cultivars and their f2 progenies were evaluated in a randomized complete block design under normal and drought stress conditions. nine sensitivity/tolerance indices were calculated for studied genotypes and stress...

• Lampricides are used to control invasive sea lamprey in the Laurentian Great Lakes. Two lampricides used, 3-trifluoromethyl-4-nitrophenol (TFM) & niclosamide. Sea and bluegill were exposed TFM, niclosamide, TFM:niclosamide mix. Brain, muscle, liver tissues collected at 6, 12, 24 h of exposure. Tissue ATP, phosphocreatine, glycogen, lactate glucose measured. Lamprey showed signs ATP synthesis ...

BACKGROUND The heat shock protein 70 (HSP70) is one kind of molecular chaperones, which plays a key role in protein metabolism under normal and stress conditions. METHODOLOGY In the present study, the mRNA expressions of HSP70 under normal physiological condition and after acute heat stress were investigated in gills of two bay scallop populations (Argopecten irradians irradians and A. i. con...

BACKGROUND Intermittent hypoxia has been suggested to increase exercise tolerance by enhancing stress resistance and improving oxygen delivery. Because the improvement of exercise tolerance reduces mortality in the elderly with and without coronary artery disease intermittent hypoxia might be a valuable preventive and therapeutic tool. However, controlled studies are lacking. METHODS AND RESU...