Water temperature is the most important factor in fish farming as changes water cause physiological stress fish. There have been few studies on responses to high temperatures, which vary with aging. This study investigated of juvenile and adult Platichthys stellatus heat stress. Plasma cortisol, glucose, lactate, lysozyme levels, antioxidant enzyme activities, expression shock proteins 70 90 (H...

objective: infectious microorganisms are major sources of illness and death worldwide, and the leading cause of death in neonates. effective vaccination of this age group is of particular importance. the lack of a response and greater susceptibility to tolerance are two major features that limit the effectiveness of vaccines in neonates. in this study we compare the cellular immune response gen...

Previously we found that 1,3-butanediol-treated mice live longer during hypoxia. We hypothesized that 1,3-butanediol could reduce the brain's accumulation of potentially cytotoxic lactate and/or elevate brain substrate availability (ketones or glucose) and thus maintain the brain's energy producing capability even during reduced oxygen availability. To test these hypotheses, whole brain metabol...

OBJECTIVE Accumulating data have recently underlined argon´s neuroprotective potential. However, to the best of our knowledge, no data are available on the cerebrovascular effects of argon (Ar) in humans. We hypothesized that argon inhalation does not affect mean blood flow velocity of the middle cerebral artery (Vmca), cerebral flow index (FI), zero flow pressure (ZFP), effective cerebral perf...

We investigated the effect of acute and acclimatory temperature on the relative contribution of g9lucose and lactate to metabolism in resting sartorius muscle of the American bullfrog (Lithobates catesbeiana). We examined the fate of these metabolites in vitro by supplying radiolabeled [(14)C]glucose, [(14)C]lactate and [(14)C]palmitate to isolated muscle bundles from frogs (1) acutely exposed ...

Microbial conversion of renewable raw materials to useful products is an important objective in industrial biotechnology. Pichia stipitis, a yeast that naturally ferments xylose, was genetically engineered for l-(+)-lactate production. We constructed a P. stipitis strain that expressed the l-lactate dehydrogenase (LDH) from Lactobacillus helveticus under the control of the P. stipitis fermentat...

Glucose tolerance test i弓 veryuseful in better understanding the stage of the regenerating process in the remnant liver during the early postoperative period after major hepatic resection. In clinical cases, glucose tolerance test could provide at least some prognostic information concerning operative risk, late survival and the likelyhood of early postoperative liver failure in hepatectorr山edp...

The lactate dehydrogenases (LDHs) in hagfish have been estimated to be the prototype of those in higher vertebrates. The effects of high hydrostatic pressure from 0.1 to 100 MPa on LDH activities from three hagfishes were examined. The LDH activities of Eptatretus burgeri, living at 45-60 m, were completely lost at 5 MPa. In contrast, LDH-A and -B in Eptatretus okinoseanus maintained 70% of the...