AIMS This study investigates the antimicrobial activity and mode of action of novel carbohydrate fatty acid (CFA) derivatives against Staphylococcus aureus and methicillin-resistant Staph. aureus (MRSA). METHODS AND RESULTS Minimum inhibitory concentrations (MICs) and the effect of CFA derivatives on lag phase were determined using a broth microdilution method. Lauric acid carbohydrate esters...

We investigated the expression and effects of hypoxia-inducible factor-1α (HIF-1α) in rat thromboangiitis obliterans (TO). Rats were divided into sham and model groups. The model group was further divided into groups based on observation duration. Lauric acid was injected below an artery clamp to simulate TO in the model group; saline was used in the sham group. Clamps were removed 15 min after...

In the horse, drug metabolism has been shown to be complex, but little is known about the proteins involved in these processes [l]. As a result of work on the purification of equine Cytochrome P450 enzymes, an epoxide hydrolase has been purified [2]. Epoxide hydrolases catalyse the hydration of biologically active epoxides formed during the metabolism of many drugs and mutagenic compounds [3]. ...

Incorporation of myristic acid onto the N terminus of a protein is a crucial modification that promotes membrane binding and correct localization of important components of signaling pathways. Recombinant expression of N-myristoylated proteins in Escherichia coli can be achieved by co-expressing yeast N-myristoyltransferase and supplementing the growth medium with myristic acid. However, undesi...

We report herein on the conversion of saturated and unsaturated fatty acids to alkanes over Pt/C in high-temperature water. The reactions were done with no added H(2) . The saturated fatty acids (stearic, palmitic, and lauric acid) gave the corresponding decarboxylation products (n-alkanes) with greater than 90 % selectivity, and the formation rates were independent of the fatty acid carbon num...

THE green turtle (Chelone mydas Linn.) is fairly widely distributed in many parts of the tropics, especially perhaps in the Indian and Pacific Oceans. Hornell [1927] states that young green turtles feed on fine confervae and on the leaves of sea-grass (Cymodocea); the adult animals live almost entirely upon this seagrass, but occasionally also on Sargasso weed. They are however occasionally car...

Recently, Temme et al (1) reported the effects of feeding diets enriched in lauric, palmitic, or olcic acid on plasma lipids in 32 normocholcstcrolemic men and women. The results showed that lauric acid was more hypercholesterolemic than palmitic acid and both were hypercholesterotemic compared with olcic acid. The subjects consumed solid food diets and the authors managed an 8% of energy excha...

Municipal sewage is a source of various lipids where the lipids can be extracted and converted to biodiesel by transesterification reaction. The present study reveals the properties of extracted Lipids like, Viscosity mmS, Density, kg/m3, Acid value mg KOH/g, Iodine value g I2/100 g, Value of saponification(mg KOH/g), Free fatty acid (%),Capric acid (%),Lauric acid (%),Myristic acids (%),Steari...