background: human granulocyte colony-stimulating factor (hg-csf) can serve as valuable biopharmaceutical for research and treatment of the human blood cancer. transplastomic plants have been emerged as a new and high potential candidate for production of recombinant biopharmaceutical proteins in comparison with transgenic plants due to extremely high level expression, biosafety and many other a...

Nowadays, marketing serves the purpose of maximizing customer lifetime value (CLV) and customer equity, which is the sum of the lifetime values of the company’s customers. But, CLV calculation encounters some difficulties which limit the usage of this technique. Nonetheless, companies looking for methods to know how to calculate their customers’ CLV. In this paper, fuzzy classification rules we...

Atrial fibrillation (AF) is characterized by disorganized rapid atrial electrical activity, which leads to impaired function, adverse hemodynamic effects, and increased thromboembolic risk. The paroxysmal forms of AF can be effectively treated with current pharmacological non-pharmacological modalities targeting the arrhythmia triggers. Persistent AF, however, more difficult treat due remodelin...

The article presents an analysis of global trends in setting the inflation target and acceptable corridor fluctuations. Inflation targeting is important attribute monetary regime targeting, its main quantitative parameter. tendency 70 countries all over world are considered, which 41 have official recognition by International Monetary Fund (IMF) regarding regime. It was found that most set at 5...

Targeting peptides are responsible for directing proteins to the appropriate subcellular location. As a group of biological sequences, targeting peptides are evolving at a relatively high rate and exhibit diversity. We investigate if evolutionary noise – simulated mutation at the molecular level – improves target classification for a neural network predictor. Comparison with the well-known Targ...

Results: The review identified only three controlled intervention studies specifically targeting Hispanic populations for weight-loss; most of the available studies were not randomized and did not assess key variables, such as acculturation, type of community of origin, level of education, etc. Most available ‘‘culturally sensitive’’ health-related interventions targeting Hispanic populations d...

METHODS. Mice without each of the four known subunits of VDCCs were generated by gene targeting and transgenic rescue (CNS1, 2) or by gene targeting alone ( 3) or were obtained from a commercial provider ( 4). Retinal function and visual sensitivity were examined by electroretinography and an active avoidance behavioral test, respectively. The structure of the retina and expression of the 1F su...

background: nutritional strategies targeting improvement of poultry performance and disease prevention are currently being developed and in this respect the dietary intake of spiced essential oils and pre-biotics in raising broilers is receiving attention. objectives: this study was conducted to compare the effects of diet containing ginger essential oils (geo) and mannan-oligosaccharide (mos) ...

Background All current anti-HIV1 therapies target the viral proteins or RNA; however targeting HIV1 at the transcriptional level of the integrated provirus has been less explored. In India, AIDS is commonly caused by HIV-1C compared to HIV-1B in developed countries. HIV1-5’LTR acts as a promoter and shows sequence variation among different clades. Transcriptional gene silencing (TGS) is a metho...