The aim of our work was to compare cytotoxic and membrane-damaging effects of O. majorana L. essential oil and linalool on Hep G2 and to investigate their possible protective (antioxidant) effects against H2O2 induced membrane damage. The oils were investigated by GC and GC-MS and antioxidant activity was evaluated by DPPH and -carotene–linoleic acid assays. Assessment of cell viability was ma...

Background: Equine wounds, particularly those involving the distal portion of the limbs, often undergo prolonged complex healing and may enter a non-healing state with obvious financial and welfare implications. Poor blood supply and lower levels of oxygen to the lower limbs lead to imbalance of growth factors related to wound healing. Decellular amniotic membrane has been widely used in soft t...

cansjera rheedii is widely used as a traditional medicine for the treatment and control of a variety of human inflammatory ailments by the fishermen of auroville.   in the present study, the anti-inflammatory and membrane stabilizing property of ethanol extract of cansjera rheedii j. gmelin (eecr) was evaluated in rat using the human red blood cells (hrbc) membrane stabilization method and carr...

a major group of drugs that have been approved for the therapy of systemic fungal infections are polyene antibiotics. amphotericin b (amb), one of the polyene antibiotics, has been used to treat serious systemic fungal infections by binding to sterols such as ergosterol in fungal cells membrane, and is believed to form pores in the membrane and create a transmembrane ion-channel. since all euka...

background: the rh antigens are expressed as parts of a protein complex in the rbc membrane. this complex is a tetramer, consisting of two molecules of rhag and two molecules of rh proteins. to express rhd in rbc membrane, expression of rhag is essential. this co-expression only occurs in the erythroid lineage. k562 cell line has an erythroid lineage. materials and methods: cord blood was used ...

the uptake and transport of 9-nitrocamptothecin (9-nc), a potent anticancer agent, across caco-2 cell monolayers was studied as a free and plga nanoparticle loaded drug. different sizes (110 to 950 nm) of 9-nitrocamptothecin nanoparticles using poly (lactic-glycolic acid) were prepared by via the nanoprecipitation method. the transport of nanoparticles across the caco-2 cell monolayer as a func...

Cansjera rheedii is widely used as a traditional medicine for the treatment and control of a variety of human inflammatory ailments by the fishermen of Auroville.   In the present study, the anti-inflammatory and membrane stabilizing property of Ethanol Extract of Cansjera rheedii J. Gmelin (EECR) was evaluated in rat using the Human Red Blood Cells (HRBC) membrane stabilization method...

The unexpected enhancement of alkalinee phosphatase (ALP) activity in the serum of a group of STZ-diabetic rats recieving the Teucrium polium extract (with hypoglycaemic property) may be attributed to its probable side effects. In order to get a more precise knowledge about this subject, we evaluated the effect of T. polium extract on the plasma membrane ALP activity of K562 cell line. Our data...