OBJECTIVES Fatigue is typically associated with multiple sclerosis (MS), but recent studies suggest that it is also a problem for patients with stroke. While a direct comparison of fatigue in, e.g., Stroke and MS is desirable, it is presently not easily possible because of different definitions and assessment tools used for the two conditions. In the present study, we therefore assessed fatigue...

Objectives: This study was designed to evaluate the psychometric features of the Persian version of the Fatigue Impact Scale (FIS-P) tool when used in Iranian MS patients. Methods: 140 MS patients and the equivalent number of healthy controls completed the following assessments: FIS-P, Fatigue Severity Scale (FSS), SF-36 questionnaire and  the Mini-Mental State Examination (MMSE). ...

Treatment with acetyl L-carnitine (ALCAR) has been shown to improve fatigue in patients with chronic fatigue syndrome, but there have been no trials on the effect of ALCAR for treating fatigue in multiple sclerosis (MS). To compare the efficacy of ALCAR with that of amantadine, one of the drugs most widely used to treat MS-related fatigue, 36 MS patients presenting fatigue were enrolled in a ra...

PURPOSE/OBJECTIVES To identify differences in fatigue, other physical symptoms, and psychological symptoms and their relationship to quality of life (QOL) during chemotherapy and as long as one year after. DESIGN Longitudinal, descriptive design embedded in a pilot intervention study. SETTING Midwestern urban oncology clinics and patient homes. SAMPLE 25 Caucasian women, aged 40-65 years ...

BACKGROUND AND PURPOSE Poststroke fatigue is common and reduces quality of life. Current evidence for intervention is limited, and this is the first placebo-controlled trial to investigate treatment of poststroke fatigue with the wakefulness promoting drug modafinil. METHODS The trial was randomized, double-blinded, and placebo-controlled. Patients were treated with 400-mg modafinil or placeb...

original article   shift work is a common work schedule that has several inappropriate consequences, the most important of which is fatigue. the aim of this study was to invest gate the impact of the shift length on the occupatio al fatigue of operators in filling stations. this cross-sectional study was carried out on operators of the filling station in national iranian oil products distributi...

BACKGROUND Fatigue is a disabling syndrome in multiple sclerosis (MS), which may be associated with inflammation and faster disease progression. OBJECTIVE To analyze the significance of cognitive fatigue for subsequent disease progression. METHOD We followed 46 MS patients and 14 healthy controls in a study over 17 months. At the beginning (t1) and at the end (t2) of the study participants ...

The role of foreign-object damage (FOD) and its effect on high-cycle fatigue (HGF) failures in a turbine engine Ti– 6Al–4V alloy is examined in the context of the use of the Kitagawa–Takahashi diagram to describe the limiting conditions for such failures. Experimentally, FOD is simulated by firing 1 and 3.2 mm diameter steel spheres onto the flat specimen surface of tensile fatigue specimens at...