AIM To evaluate the clinical and anatomical outcomes of pars plana vitrectomy and gas tamponade without internal limiting membrane (ILM) peeling in symptomatic patients caused by myopic foveoschisis. METHODS Nine eyes in eight highly myopic patients who had myopic foveoschisis with foveal detachment underwent vitrectomy without ILM peeling followed by gas tamponade. Main outcome measures incl...

PURPOSE Proper visual transmission depends on the retinal ON and OFF pathways. We used Vsx1-/- mice with a retinal OFF visual pathway defect to determine the role of OFF pathway signaling in refractive development (RD) of the eye. METHODS Refractive development was measured every 2 weeks in Vsx1-/-, Vsx1+/+ (both on 129S1/Sv background), and commonly used C57BL/6J mice from 4 to 12 weeks of a...

Purpose: To compare retinal nerve fiber layer (RNFL) profile in subjects with myopia and emmetropia using GDx variable corneal compensator (VCC) Methods: Besides ophthalmologic standard examination (refraction, visual acuity and slit-lamp examination, applanation tonometry, and funduscopy), perimetry and scanning laser polarimetry (SLP) were performed. 171 healthy age-matched subjects with low ...

PURPOSES To determine axial, vertical, and horizontal eye dimensions in myopic and emmetropic eyes by using magnetic resonance imaging (MRI) and to relate these to different ocular expansion models of myopia development. METHODS The internal length (cornea to retina), height and width (both retina to retina) were measured in emmetropic and myopic eyes (up to -12 D) of 88 participants aged 18 ...

Purpose. To examine biomechanical parameters of the cornea in myopic eyes and their relationship with the degree of myopia in a western healthy population. Methods. Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann correlated intraocular pressure (IOP), and corneal compensated IOP (IOPcc) were measured using the ocular response analyzer (ORA) in 312 eyes of 177 Spanish subjects...

Axial myopia is a risk factor for the development of many concomitant pathological conditions, including those likely to lead an irreversible loss visual functions. Until now, specialists disagree about terminology and approaches classification myopia. We propose critical analysis state-of-the-art research use them offer, definitions such conditions as “myopic macular degeneration (myopic macul...

PURPOSE To determine how formation of an acquired myopic crescent adjacent to the optic disc affects metabolic activity in the primary visual cortex. DESIGN Laboratory animal study. PARTICIPANTS Three macaque monkeys. METHODS The blind spot region in the primary visual cortex was labeled by cytochrome oxidase (CO) histochemistry analysis or [(3)H]proline autoradiography. MAIN OUTCOME ME...

This study investigated differences in geometrical properties and optical aberrations between a group of hyperopes and myopes (age-matched 30.3+/-5.2 and 30.5+/-3.8 years old, respectively, and with similar absolute refractive error 3.0+/-2.0 and -3.3+/-2.0, respectively). Axial length (AL) was measured by means of optical biometry, and corneal apical radius of curvature (CR) and asphericity (Q...

PURPOSE To evaluate the accuracy of postoperative refractive outcomes of combined phacovitrectomy for epiretinal membrane (ERM) in comparison to cataract surgery alone. MATERIALS AND METHODS Thirty-nine eyes that underwent combined phacovitrectomy with intraocular lens (IOL) implantation for cataract and ERM (combined surgery group) and 39 eyes that received phacoemulsification for cataract (...