نتایج جستجو برای: nω hydroxy nor l arginine

تعداد نتایج: 764458  

2013
Anna P. Ralph Govert Waramori Gysje J. Pontororing Enny Kenangalem Andri Wiguna Emiliana Tjitra Sandjaja Dina B. Lolong Tsin W. Yeo Mark D. Chatfield Retno K. Soemanto Ivan Bastian Richard Lumb Graeme P. Maguire John Eisman Ric N. Price Peter S. Morris Paul M. Kelly Nicholas M. Anstey

BACKGROUND Vitamin D (vitD) and L-arginine have important antimycobacterial effects in humans. Adjunctive therapy with these agents has the potential to improve outcomes in active tuberculosis (TB). METHODS In a 4-arm randomised, double-blind, placebo-controlled factorial trial in adults with smear-positive pulmonary tuberculosis (PTB) in Timika, Indonesia, we tested the effect of oral adjunc...

2003
Gary M. MALVIN Nathan CECAVA Leif D. NELIN

We investigated nitric oxide (NO) production in Paramecium caudatum, and the role of NO production in population growth in culture and thermoregulation. Nitrite (NO2 -) concentration in media containing P. caudatum [6350 ± 390 (SD) paramecia/ml] was 2.37 ± 0.53 μM after 6 h, compared to 0.16 ± 0.06 μM in media alone (p<0.005), and the NO synthase (NOS) inhibitor, Nω-nitro-L-arginine methylester...

ژورنال: :نشریه دانشگاه علوم پزشکی البرز 0
مریم خانه‎زاد m. khanehzad سید محمد حسین نوری موگهی m.h. noori-moogahi 2. professor in anatomy, anatomy department, faculty of medicine, tehran university of medical sciences, tehran, iranگروه آناتومی، دانشکده علوم پزشکی، دانشگاه علوم پزشکی تهران، تهران، ایران ثریا پروری s. parvari

مقدمه: نیتریک اکساید (no) مولکول کوچک چربی دوستی است که توسط آنزیم نیتریک اکساید سنتاز از پیش‎ساز l-arginine در بسیاری از اندام‎های بدن تولید می شود. هدف: با توجه به نقش مهم نیتریک اکساید در بسیاری از فرایندهای بیولوژیک بدن خصوصاً سیستم قلبی- عروقی، هدف از انجام این مطالعه بررسی اثرات تحریکی و مهاری آن بر قلب است. مواد و روش ها: 40 سر موش صحرایی ماده نژاد ویستار با وزن 200-250 گرم و سن متوسط 8 ه...

Journal: :The Journal of pharmacology and experimental therapeutics 2011
Olga Lekontseva Subhadeep Chakrabarti Yanyan Jiang Christopher C Cheung Sandra T Davidge

Estrogen has antihypertensive and vasorelaxing properties, partly via activation of endothelial nitric-oxide synthase (eNOS). Recently, neuronal nitric-oxide synthase (nNOS) has been detected in vascular cells, although the significance of this is unclear. Estrogen was found to stimulate nNOS in certain cultured cells. We hypothesized that estrogen regulates vascular tone partly via endothelium...

Journal: :Acta neurobiologiae experimentalis 1998
A Jachimowicz Z Hoły K Wiśniewski

In this study we tested the hypothesis that nitric oxide (NO), which function as a novel type of inter-cellular messenger in the central nervous system (CNS) participated in the facilitator effect of arginine vasopressin (AVP) on learning and memory. Recent investigations have provided evidences that inhibition of NO synthesis attenuated the vasodilatation caused by AVP, and inhibited the impro...

Journal: :American journal of hypertension 2014
Andréia Machado Cardoso Fátima Husein Abdalla Margarete Dulce Bagatini Caroline Curry Martins Fernando da Silva Fiorin Jucimara Baldissarelli Pauline Costa Fábio Fernandes de Mello Amanda Maino Fiorenza Jonas Daci da Silva Serres Jamile Fabbrin Gonçalves Heloísa Chaves Luiz Fernando Freire Royes Adriane Belló-Klein Vera Maria Morsch Maria Rosa Chitolina Schetinger

BACKGROUND Cholinergic enzyme activities are altered in hypertension, reflecting a low-grade inflammation. Regular physical exercise exerts anti-inflammatory effects and has been described as a coadjutant in the treatment of hypertension. In this study, we investigated the effect of 6 weeks of swimming training on cholinergic enzyme activities (acetylcholinesterase and butyrylcholinesterase) in...

Introduction: Cisplatin is a widely used anti-cancer drug, which its application is limited by nephrotoxicity. In this study, the effect of pretreatment with different l-arginine doses on Cisplatin-induced renal functional injury was investigated. Methods: 63 male rats were divided into 7 groups: In groups 3, 4, 5 and 6, 60 min before the Cisplatin injection (5mg/kg); L-Arginine with doses o...

Nurany, Maryam, Ebrahimi, Fatemeh , Mazloumi Kiapey, Seyedeh Shabnam , Pahlavani, Naseh , Sadeghi, Omid ,

Introduction: Due to controversies in different studies about the effects of L-arginine supplementation on athletic performance and cardiovascular risk factors, this study aimed to review the current evidence on the effects of L-arginine supplementation on athletic performance and cardiovascular risk factors. Methods: This study was done to summarize findings from earlier evidence on the effect...

Journal: :basic and clinical neuroscience 0
mohammad-reza zarrindast bita hamidi mohammad sharifzadeh mousa sahebgharani soheila fazli-tabaei

in the present study, interactions between lead exposure with nitric oxide precursor (l-arginine) or nitric oxide synthase (nos) inhibitor (l-name) on naloxone-induced jumping and diarrhea in morphine-dependent mice were examined. chronic lead acetate (0.05%) exposure altered naloxone-induced jumping and diarrhea in mice. jumping was decreased after 7 days and was unchanged 14 and 28 days after...

2012
Tsuyoshi Kurokawa Jun An Koji Tsunekawa Yoshiharu Shimomura Shunsuke Kazama Naohisa Ishikawa Toshiaki Nonami Satoru Sugiyama

BACKGROUND Nitric oxide (NO) has been reported to be a key mediator in hepatocyte proliferation during liver regeneration. NO is the oxidative metabolite of L-arginine, and is produced by a family of enzymes, collective termed nitric oxide synthase (NOS). Thus, administration of L-arginine might enhance liver regeneration after a hepatectomy. Another amino acid, L-glutamine, which plays an impo...

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