This study showed that nasal allergy patients have increased nasal airway resistance and tissue kallikrein activity in nasal lavage in accordance with the severity of symptoms. Nasal airway resistance and tissue kallikrein activity were significantly increased in the nasal lavage collected 15 min after antigen challenge, placement of a disk containing house dust antigen. The free kinin level in...

BACKGROUND A clinical test that could inform the clinician about the severity of a patient's nasal symptoms and health-related quality of life (QOL) would be very useful. OBJECTIVE We attempted to determine whether, in patients with perennial allergic rhinitis, nasal challenge with histamine could be used to estimate daily symptoms and QOL. METHODS Forty-eight patients with perennial allerg...

The nasal cavity is susceptible to chemically induced injury as a result of exposure to inhaled irritants. Some responses of the nasal mucosa to inhaled toxicants are species specific. These species-related differences in response may be due to variations in structural, physiologic, and biochemical factors, such as gross nasal cavity structure, distribution of luminal epithelial cell population...

he nasal valve is the narrowest region of the nasal passage, nd the main, flow-limiting segment of the nasal cavity.1,2 ariations in the size and shape of the nasal cavity affect he rate and pattern of airflow and influence nasal function. t therefore seems likely that improved nasal patency may lleviate snoring and sleep-disordered breathing.3,4 Traditional surgical management of nasal obstruc...

Some aerodynamic approaches to the estimation of velopharyngeal opening (VPO) are confounded by oral impedance, which varies with tongue height and affects nasal flow. Here the relationship between nasal flow and tongue height is investigated using a synchronized EMAaerodynamics system. A corpus of Hindi nasal and oral vowels is examined. Tongue height and nasal flow are weakly but positively c...

As the main mucosal immune inductive site of nasal cavity, nasal-associated lymphoid tissue (NALT) plays an important role in both antigen recognition and immune activation after intranasal immunization. However, the efficiency of intranasal vaccines is commonly restricted by the insufficient intake of antigen by the nasal mucosa, resulting from the nasal mucosal barrier and the nasal mucocilia...

OBJECTIVES We assessed the efficacy of different forms of fluticasone propionate in the treatment of bilateral nasal polyposis in adult patients. PATIENTS AND METHODS This double-blind, randomized, parallel group study included 34 patients, aged 16 years or over, with a diagnosis of bilateral nasal polyposis. The patients were randomized to three groups to receive fluticasone propionate in th...

background: fetal nasal bone assessment is a non-invasive procedure that helps provide even greater assurance to patients undergoing their first trimester risk assessment for aneuploidies. absence or presence of this factor is different in some races. objective: the study was aimed to evaluate nasal bone in the first trimester of pregnancy in the indigenous population of khuzestan province, and...

Nasal valve collapse is a primary cause of nasal obstruction. Patients with airway obstruction suffer from variety symptoms that affect quality life including congestion, headache, sleep problems, daytime sleepiness, and snoring.

Local Allergic Rhinitis (LAR) is an emerging disease. However, its incidence in the pediatric population has not yet been studied. The gold-standard for the diagnosis is the nasal provocation test that is not everywhere available and difficult to apply in children. The aim of our study is to evaluate the nasal lavage fluid IgE as a biomarker of LAR in children. 54 pediatric patients [IQR 4.0-12...