Objective(s): Nanocarriers are drug delivery vehicles, which have attracted the attention of researchers in recent years, particularly in cancer treatment. The encapsulation of anticancer drugs using protein nanocages is considered to be an optimal approach to reducing drug side-effects and increasing the bioavailability of anticancer drugs. Epirubicin (EPR) is an active chemotherapeutic medica...

abstract background & aim: recent increase of hormonal disorders in human may be correlated to the increased exposure to electromagnetic fields produced by various instruments, including cell phones. thyroid gland is one of the organs most likely to be exposed to cell phone radiation. whereas garlic is known as reducing risk factors for various diseases. the aim of this study is to assess the a...

The 21st L H Gray Conference, organised by the L H Gray Trust with the Society for Radiological Protection, brought together international experts in radiobiology, epidemiology and risk assessment, and scientists involved in diagnostic and therapeutic radiation exposure. The meeting — held in Edinburgh, Scotland, on 4–6 June 2008 — aimed to raise awareness, educate and share knowledge of import...

BACKGROUND The biological effects of ionizing radiation have long been thought to results from direct targeting of the nucleus leading to DNA damage. Over the years, a number of non-targeted or epigenetic effects of radiation exposure have been reported where genetic damage occurs in cells that are not directly irradiated but respond to signals transmitted from irradiated cells, a phenomenon te...

The risks of exposure to low dose ionizing radiation (below 100 mSv) are estimated by extrapolating from data obtained after exposure to high dose radiation, using a linear no-threshold model (LNT model). However, the validity of using this dose-response model is controversial because evidence accumulated over the past decade has indicated that living organisms, including humans, respond differ...

Background: The development of methods to alleviate radiation-induced health effects is important for the practical use of radiation therapy and for understanding the molecular mechanisms mediating these effects. Here, we examined the protective capability of N-acetylcysteine (NAC) on life-shortening effects induced by continuous low dose-rate gamma-ray exposure in mice. Materials and Methods: ...