BRD4 is implicated in the pathogenesis of a number of different cancers. It is also the target of translocation t(15;19) that accounts for the highly aggressive NUT midline carcinoma (NMC). We discovered that t(15;19) NMC cells display the ability to grow into stem cell–like spheres and express an exceptionally high level of the stem cell marker, SOX2. The BRD4-NUT fusion oncogene resulting fro...

This study aimed to assess the association of various types of nut per se, and total nut consumption with the incidence of metabolic syndrome (MetS). A 6.2 ± 0.7-year population-based prospective study was conducted among 1265 adults, aged 19-74 years, participants of the Tehran Lipid and Glucose Study. A 168-item semi-quantitative food frequency questionnaire was used to collect information on...

Reproductive output by the Florida-endemic scrub hickory (Carya floridana Sargent) was studied over a 28-yr period in three south-central Florida vegetation associations: southern ridge sandhill, sand pine scrub, and scrubby flatwoods. The objectives were to describe multi-annual patterns of variation in nut production, identify factors involved in this variation, and investigate differences in...

OBJECTIVE To determine the prevalence of and characteristics associated with Sri Lankan adolescents' chewing of areca. BASIC RESEARCH DESIGN Cross-sectional descriptive study based on a self-administered questionnaire. PARTICIPANTS 633, 15-year-olds in the Bandarawela education zone of Sri Lanka. RESULTS Nearly 7% of the sample were current chewers of arecanut and 1% of commercially avail...

Colloidal capsules can sustain an external osmotic pressure; however, for a sufficiently large pressure, they will ultimately buckle. This process can be strongly influenced by structural inhomogeneities in the capsule shells. We explore how the time delay before the onset of buckling decreases as the shells are made more inhomogeneous; this behavior can be quantitatively understood by coupling...

Pistachio suffers from some physiological disorders such as fruit abscission, endocarp lesion, blankness, non-split, early-split and deformed nuts. In this experiment, the effects of calcium nitrate (2 gr/lit), calcium chloride (2 gr/lit), boric acid (200 ppm) and their combination treatments were investigated on physiological disorders of ‘Kaleh-Ghoochi’ pistachio. Foliar application was appli...

Nuclear protein of the testis (NUT) midline carcinomas are rare aggressive carcinomas characterized by chromosomal rearrangements that involve the gene encoding the NUT. This article reviews the clinicopathologic features and the differential diagnosis of these malignancies.

The maximal globally hyperbolic development of non-Taub-NUT Bianchi IX vacuum initial data and of non-NUT Bianchi VIII vacuum initial data is C2-inextendible. Furthermore, a curvature invariant is unbounded in the incomplete directions of inextendible causal geodesics.

OBJECTIVE To assess the association, in a Mediterranean population, between nut consumption and risk of weight gain (at least 5 kg) or the risk of becoming overweight/obese. RESEARCH METHODS AND PROCEDURES The Seguimiento Universidad de Navarra project is a prospective cohort of 8865 adult men and women who completed a follow-up questionnaire after a median of 28 months. Dietary habits were a...