INTRODUCTION Addiction imposes a large medical, social and economic burden on societies. Currently, there is no effective treatment for addiction. Our struggle to decipher the different mechanisms involved in addiction requires a proper understanding of the brain regions which promote this devastating behavior. Previous studies have shown a pivotal role for insula in cigarette smoking. In this ...

OBJECTIVES Serum adiponectin and leptin levels have been shown to be related to obesity, insulin resistance and cardiovascular diseases (CVD). Opium addiction has a positive association with endocrine system disorders. The relationship between adipokines and opium addiction is unclear. In the present study, we aimed to determine serum adiponectin and leptin levels in opium addicted subjects. ...

background: colorectal cancers (crcs) including colon, rectum and anal cancers are the third most prevalent cancers in the world. there are strong evidence showing the risk of the cigarette smoking, alcohol use, low physical activity and some types of diets in crcs; however, few studies explored the relationship between opium use and crcs. this study aimed to investigate the association between...

OBJECTIVE The association between opium use and bladder cancer has been investigated in many studies, with varying reporting results reported. This study aims to estimate the total odds ratio for the association between bladder cancer and opium consumption using meta-analysis. METHODS The study was designed according to PRISMA guidelines. Two independent researchers searched for the relevant ...

BACKGROUND The main source of studies about effects of opium consumption on heart and brain attacks originates from Iran Therefore the aim of the present study was to assess opium addiction as a probable influencing factor for ischemic heart disease and ischemic stroke. MATERIALS AND METHODS A cross-sectional study was carried out in two Cardiology and Neurology clinics in Eastern Iran in 201...

Background: Fertility is considered as a life conservative phenomenon among married couples which can be obliterated by various conditions affecting both males and females. In the other hand addiction is a problem which increasingly developed among the various populations throughout the world, and there are evidences that addiction may affect the hypothalamous-pituitary-gonadal axis and sexual ...

opium-eaters brought to the jail to undergo sentence of imprisonment. The people of Sagor were worse off as regards opium taking than those of Narsingpur. My rule of practice was to stop opium completely at once. It is true that the prisoners complained of excruciating pain for a day or two, but this was, I think, more imaginary than real, or rather the sensation of a mind weakened and imbecile...

Opium (powdered poppy Capsules) mixed with sugars and other plant products is a popular home made remedy for colic, cough and tonics for infants and children in Baluchistan. Over a period of 7 years (1977.1983) 28 children between the ages of I month to 5 years were admitted in Civil Hospital Quetta due to opium poisoning accounting for 0.16% of all paediatric admissions during the same period....

We model the economic incentives surrounding opium crop production in Afghanistan. Specifically, we examine the impact of eradication policies when opium is used as a means of obtaining credit, and when the crops are produced in sharecropping arrangements. The analysis suggests that when perfect credit markets are available, an increased risk of eradication will lead to less land being allocate...