Chloroperoxidase and horseradish peroxidase use NaClOz as both the oxidant and the halogen donor for the peroxidative chlorination of monochlorodimedone. Previous studies have shown that both horseradish peroxidase and chloroperoxidase can catalyze iodination reactions with hydrogen peroxide as the oxidant; however, only chloroperoxidase catalyzes chlorination reactions under these conditions. ...

Objective: This study aimed to investigate the relationship between acute-phase reactants and oxidative stress epilepsy. Methods: The patient group consisted of 67 patients who applied Pediatric Neurology outpatient clinic were diagnosed with generalized type epilepsy according ILAE classification, 33 receiving monotherapy 34 antiepileptic medication in form polytherapy. control included 30 hea...

The identification of endothelial progenitor cells (EPCs) has led to a significant paradigm in the field of vascular biology and opened a door to the development of new therapeutic approaches. Based on the current evidence, it appears that EPCs may make both direct contribution to neovascularization and indirectly promote the angiogenic function of local endothelial cells via secretion of angio...

BACKGROUND HIV-infected individuals are at increased risk for acute and chronic airway disease even though there is no evidence that the virus can infect the lung epithelium. Although HIV-related proteins including gp120 and Tat can directly cause oxidant stress and cellular dysfunction, their effects in the lung are unknown. The goal of this study was to determine the effects of HIV-1 transgen...

The functionalization of C?H bonds in light alkanes, particularly to form C?N bonds, remains a challenge. We report the dehydrogenative coupling amides with C1–C4 hydrocarbons N-alkyl amide products tBuOOtBu as oxidant, and copper complex phenanthroline-type ligand catalyst. reactions occurred good yields benzene or supercritical carbon dioxide solvents. This strategy allowed for determination ...

THIS ISSUE of the American Journal of Physiology-Lung Cellular and Molecular Physiology features five articles that provide new insights into the mechanisms and cellular pathways regulating oxidant signaling in lungs. Reactive oxygen species (ROS) from cellular sources have been regarded as toxic byproducts of metabolism with the potential to cause damage to lipids, proteins, and DNA (22). Oxid...

Asthma is a chronic inflammatory disease of the respiratory tract of unknown aetiology. In severe asthma airway diathesis is profound, and thus apparent. Recently, however, evidence has indicated that specific inflammatory abnormalities exist even in the airways of subjects with mild disease. As inflammation is often associated with an increased generation of reactive oxygen species (ROS), and ...

several lichen species have been used for medicinal purposes throughout the ages, and they were reported to be effective in the treatment of different disorders including tuberculosis, hemorrhoids, ulcer, dysentery and cancer. it is revealed that they may be easily accessible sources of natural drugs that could be used as a possible food supplement or in pharmaceutical industry after their safe...

It is thought that reactive oxygen species (ROS) participate in the inflammation which characterizes asthma, but the evidence supporting this contention is incomplete. F 2 -isoprostanes (F 2 -IsoPs) are arachidonate products formed on membrane phospholipids by the action of ROS and thereby represent a quantitative measure of oxidant stress in vivo. Using a mass spectrometric assay we measured u...