This paper aims to develop a multi-objective model for scheduling cargo trains faced by the costs of tardiness and earliness, time limitations, queue priority and limited station lines. Based upon the Islamic Republic of Iran Railway Corporation (IRIRC) regulations, passenger trains enjoy priority over other trains for departure. Therefore, the timetable of cargo trains must be determined based...

after 1860’s the railway systems has started to be used in urban transportation in the world. however, especially after the 1950’s, automobile usage has been increased quickly. thus the dense of transportation has started to move from railway systems to the ones with rubber tire vehicles in istanbul. traffic density in urban transportation has started to be experienced since 1950 with the incre...

The passenger vehicle occupant fatality rate at nighttime is about three times higher than the daytime rate. In 2005, among the fatally injured passenger vehicle occupants, the proportion of unrestrained occupants was much higher during nighttime than daytime. Also during nighttime, among passenger vehicle occupants killed in crashes, alcohol involvement, speeding, and single-­vehicle crash fat...


 Facilities at the airport are divided into two main parts consisting of land side and air side. Existing facilities on consist of: passenger terminal, cargo operational building, traffic control tower or Air Traffic Control (ATC), SAR (Search Rescue) meteorological main/VIP class entrance , fueling as well administrative office buildings. While runways, taxiways, aircraft parking areas, ...

Moraxella catarrhalis O35E was shown to synthesize a 105-kDa protein that has similarity to both acid phosphatases and autotransporters. The N-terminal portion of the M. catarrhalis acid phosphatase A (MapA) was most similar (the BLAST probability score was 10(-10)) to bacterial class A nonspecific acid phosphatases. The central region of the MapA protein had similarity to passenger domains of ...

Aurora kinases possess a conserved catalytic domain (CD) and a N-terminal domain (ND) that varies in size and sequence. We have previously reported that the N-terminal domain of AuroraA (AurA) participates in the localization of the kinase to the centrosome in interphase. AuroraB (AurB) is a chromosome passenger protein and its N-terminal domain is not necessary for its localization or function...

The Arabidopsis thaliana CUTA gene encodes a 182-amino-acid-long putative precursor of a chloroplast protein with high sequence similarity to evolutionarily conserved prokaryotic proteins implicated in copper tolerance. Northern analysis indicates that AtCUTA mRNA is expressed in all major tissue types. Analysis of cDNA clones and RT-PCR with total mRNA revealed alternative splicing of AtCUTA b...

Recent evidence indicates that shRNAs with a relatively short basepaired stem do not require Dicer processing, but instead are processed by the Argonaute 2 protein (Ago2). We named these molecules AgoshRNAs as both their processing and silencing function are mediated by Ago2. This alternative processing yields only a single RNA guide strand, which can avoid off-target effects induced by the pas...

The Gram-negative periodontopathogen Aggregatibacter actinomycetemcomitans (Aa) binds selectively to buccal epithelial cells (BECs) of human and Old World primates by means of the outer-membrane autotransporter protein Aae. We speculated that the exposed N-terminal portion of the passenger domain of Aae would mediate binding to BECs. By using a series of plasmids that express full-length or tru...