A gas chromatographic method using a capillary column with electron capture detection was developed for the simultaneous determination of 3 nitromusk fragrance ingredients: musk ambrette (MA), musk xylol (MX), and musk ketone (MK), in fragrance products. The accuracy of the method was determined by recovery of each nitromusk from fortified fragrance products at 3 different concentrations. Recov...

he interest in using and conducting clinical trials in developing world is rising promptly. Knowing the importance of this kind of research in generating therapeutic evidence, many clinical researchers in developing countries including Iran are getting involved in performing clinical trials. Authors performed a quick search in ISI Web of Knowledge database (May 2008) which shows interesting res...

Sera from sheep and goats in northern Somalia which are exported to countries of the Persian Gulf are systematically checked for brucellosis by local veterinary teams. The standard test used is rapid seroagglutination using the Rose Bengal test (RBT) and seropositive animals are not exported. In order to assess the reliability of the serological results, three randomised batches of samples (653...

This paper proposes an innovative approach to improve the classification performance of Persian texts. The proposed method uses a thesaurus as a helpful knowledge to obtain more representative word-frequencies in the corpus. Two types of word relationships are considered in our used thesaurus. This is the first attempt to use a Persian thesaurus in the field of Persian information retrieval. Ex...

In this article, we have introduced the first parallel corpus of Persian with more than 10 other European languages. This article describes primary steps toward preparing a Basic Language Resources Kit (BLARK) for Persian. Up to now, we have proposed morphosyntactic specification of Persian based on EAGLE/MULTEXT guidelines and specific resources of MULTEXT-East. The article introduces Persian ...

House musk shrews (Suncus murinus) are known to have an alimentary canal more structurally similar to that of human beings than rats or mice (Kurohmaru, 1985), to be sensitive to motion sickness (Kaji et al. 1990), and to be more resistant to Xrays than C3Hf/He mice (Tsubouchi et al., 1984). They have been widely used in studies on disease models for motion sickness, gastric cancer, and hematop...

The development of the neuromuscular synapse depends on signaling processes that involve protein phosphorylation as a crucial regulatory event. Muscle-specific kinase (MuSK) is the key signaling molecule at the neuromuscular synapse whose activity is required for the formation of a mature and functional synapse. However, the signaling cascade downstream of MuSK and the regulation of the differe...

Myasthenia gravis is an autoimmune disease of the neuromuscular junction (NMJ) caused by antibodies that attack components of the postsynaptic membrane, impair neuromuscular transmission, and lead to weakness and fatigue of skeletal muscle. This can be generalised or localised to certain muscle groups, and involvement of the bulbar and respiratory muscles can be life threatening. The pathogenes...

Congenital myasthenic syndromes (CMS) are heterogeneous disorders in which the safety margin of neuromuscular transmission is compromised by one or more specific mechanisms. Using Sanger and exome sequencing in a CMS patient, we identified two heteroallelic mutations, p.Glu1233Lys and p.Arg1277His, in LRP4 coding for the postsynaptic low-density lipoprotein receptor-related protein 4. LRP4, exp...