BACKGROUND Propofol is a widely used, short-acting, and intravenously administered hypnotic agent with notable antioxidant and free radical scavenging activities. However, there are relatively few kinetic studies on the free radical scavenging ability of propofol. The goal of this study is to evaluate the kinetics of propofol scavenging 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (A...

In this paper we have studied the effect of copolymerization of a non-ionic but hydrophilic monomer on the interfacial properties of the latex surface. Hydrophilic polymer colloids were prepared by the emulsifier-free emulsion copolymerization of styrene and 2-hydroxyethyl methacrylate (HEMA) with potassium persulfate as initiator. The copolymer compositions were evaluated by 1H nuclear magneti...

To develop materials with improved controllability and specificity, we have investigated composite hydrogels with temperature-sensitive properties using photo cross-linking. Specifically, our novel composite materials are composed of nanoparticles made of poly(N-isopropylacrylamide) (PNIPAAm), temperature-sensitive hydrogels, and a photo cross-linker, poly(ethylene glycol) diacrylate (PEGDA). P...

Some pH responsive polymeric matrix of Linseed (Linum usitatissimum), L. hydrogel (LSH) was prepared by free radical polymerization using potassium persulfate (KPS) as an initiator, N,N-methylene bisacrylamide (MBA) as a crosslinker, acrylic acid (AA) and methacrylic acid (MAA) as monomers; while ketoprofen was used as a model drug. Different formulations of LSH-co-AA and LSH-co-MAA were formul...

Neuronal nitric oxide synthase (NOS I) has been shown to generate nitric oxide (NO*) and superoxide (O(2)* during enzymatic cycling, and the ratio of each free radical is dependent upon the concentration of L-arginine. Using spin trapping and electron paramagnetic resonance spectroscopy, we detected alpha-hydroxyethyl radical (CH(3)*CHOH), produced during the NOS I metabolism of ethanol (EtOH)....

The aim of this study was to investigate and compare the release rates of chlorhexidine (CX) base entrapped in the polymeric beads of modified poly-N-isopropylacrylamides (pNIPAMs) at temperatures below and over the volume phase transition temperature (VPTT) of synthesized polymers: pNIPAM-A with terminal anionic groups resulting from potassium persulfate initiator, pNIPAM-B with cationic amidi...

Hydrogels are commonly used as scaffolds for the preparation of three-dimensional tissue constructs and encapsulation delivery cells in regenerative medicine. Polyesters an attractive class polymers hydrogel preparation. However, most polyesters have hydrophobic backbones lack pendent groups that can be chemically functionalized. We describe here development water-soluble based on aspartic acid...

The aqueous radical homopolymerization of vinylidene fluoride (VDF), as well its copolymerizations with hexafluoropropylene (HFP) or perfluoromethyl vinyl ether (PMVE), and terpolymerization HFP PMVE, initiated by trifluoromethyl radicals (•CF3), generated from the ammonium persulfate (APS) potassium sulfinate (CF3SO2K) redox system are presented. optimization experimental conditions in terms i...