Uniparental disomy (UPD) refers to the presence of two copies of a chromosome from one parent and none from the other parent. In genetic studies of UPDs, many genetic markers are usually used to identify the stage of nondisjunction that leads to UPD and to uncover the associated unusual patterns of recombinations. However, genetic information in such data has not been fully utilized because of ...

background: the goal of this investigation was to compare the behavioral and physiological effects of three sedative drug regimens: oral meperidine (om), submucosal meperidine (sm) and oral midazolam (m) in healthy pediatric patients. materials and methods: this study sample consisted of thirty children aged 24-72 months (mean = 41.1) exhibiting definitely negative behavior. three sedative regi...

We present an analysis of crossover interference over the entire human genome, on the basis of genotype data from more than 8,000 polymorphisms in eight CEPH families. Overwhelming evidence was found for strong positive crossover interference, with average strength lying between the levels of interference implied by the Kosambi and Carter-Falconer map functions. Five mathematical models of inte...

Healthy human postural sway exhibits strong intermittency, reflecting a richly interactive foundation of control. From linear perspective, intermittent fluctuations might be interpreted as engagement and disengagement complementary control processes at distinct timescales or from nonlinear cascade-like interactions across many once. The diverse entailed by multiplicative dynamics suggest specif...

Purpose: A theory states that strong core stability allows athletes to fully transfer forces from the upper extremities to lower extremities, and finally to the ground. On the contrary, weak core stability causes alterations in transferring forces, reduces sport performance, and increases risk for injury, especially in the lower extremities. Therefore, the current study investigated the relatio...

Estimation of distribution algorithms (EDA) are similar to genetic algorithms except that they replace crossover and mutation with sampling from an estimated probability distribution. We develop a framework for estimation of distribution algorithms based on the principle of maximum entropy and the conservation of schema frequencies. An algorithm of this type gives better performance than a stan...

A novel model matching method based on improved genetic algorithm is presented in this paper to improve efficiency of matching process for 3D face synthesis. New method is independent from initial values and more robust than stochastic gradient descent method. Improved genetic algorithm has strong global searching ability. Crossover and mutation probability are regulated during optimization pro...

In social networks, individual heterogeneity is widely existed, and an often tends to contact more frequently with friends of similar status or opinion. It worth noting that the preference characteristic among heterogeneous individuals will have a significant effect on contagions. Thus, we propose contagion model which takes influence into account, make theoretical analysis spreading process by...

Exciton-exciton recombination in isolated semiconducting single-walled carbon nanotubes was studied using femtosecond transient absorption. Under sufficient excitation to saturate the optical absorption, we observed an abrupt transition between reaction- and diffusion-limited kinetics, arising from reactions between incoherent localized excitons with a finite probability of ~0.2 per encounter. ...