In the present study, we investigated whether erythropoietin (Epo) has a protective effect against cytotoxicity induced by interferon-gamma (IFN-gamma ) and lipopolysaccharide (LPS) in primary rat oligodendrocyte cultures. The possible modulatory effect of erythropoietin on inducible nitric oxide synthase (iNOS) mRNA expression and nitrite production were also analyzed. Erythropoietin exerted a...

introduction: despite extensive studies about effects of crataegus monogyna on cardiovascular diseases yet, a few study has been undertaken antiarrhythmic property of this plant. aims of the present study were: 1) to determine the protective role of methanolic extract of c.monogyna on the rate-dependent model and the concealed conduction . 2) to explore the role of na+-k+ a tpase in the protect...

alzheimer’s disease (ad) is a neurodegenerative disease that was characterized with deposit of beta amyloid (aβ) aggregate in senile plaque. oxidative damage to neurons and loss of cholinergic neurons in forebrain region are observed in this disease. melissa officinalis is a medicinal plant from lamiaceae family, used traditionally in the treatment of cognitive disorders. it has cholinomimetic ...

background family plays an important role in helping adolescent acquiring skills or strengthening their characters. objectives we aimed to evaluate the influences of family factors, risky and protective, on adolescent health-risk behavior (hrb). patients and methods in this cross-sectional study, students of high schools in kerman, iran at all levels participated, during november 2011 till dece...

the present study was aimed at elucidating the protective effect of ferulic acid (fa), a natural polyphenol against nicotine-induced tissue damage, including lung, liver and kidney of experimental rats. female albino rats of wistar stain were used for the experimental study. lung toxicity was induced by subcutaneous injection of nicotine at a dose of 2.5 mg/kg body weight (5 days a week, for 22...

BACKGROUND The dose-limiting toxicity of doxorubicin on hematopoietic stem cells reduces the maximum benefit from this powerful drug. Melatonin may play a role in reducing this toxicity. MATERIALS AND METHODS Melatonin at 10 microM was used while challenging human peripheral blood stem cells (PBSC) with doxorubicin (0.6 microM and 1 microM), and colony formation was used to evaluate the prote...

Epidemiologic evidence of a protective effect of vitamin C for non-hormone-dependent cancers is strong. Of the 46 such studies in which a dietary vitamin C index was calculated, 33 found statistically significant protection, with high intake conferring approximately a twofold protective effect compared with low intake. Of 29 additional studies that assessed fruit intake, 21 found significant pr...

We analyzed the effectiveness of personal protective equipment and oseltamivir use during the 2003 avian influenza A (H7N7) epidemic in the Netherlands by linking databases containing information about farm visits, human infections, and use of oseltamivir and personal protective equipment. Using a stringent case definition, based on self-reported conjunctivitis combined with a positive hemagglu...

Liver is considered to be one of the vital organs which helps in maintaining the health of body. Yakrit (liver) is being described right from the vedic period. Modern lifestyles can overstress the liver and make it malfunctioning. No significant and safe hepato-protective drugs are available in modern therapeutics. The nature has bestowed some plants with the property to prevent, treat and cure...