background: pain adversely affects cancer patients quality of life . knowing different sources of pain helps physicians and patients to manage it. the aim of this study was investigating physical factors affecting pain in iranian cancer patients. method: this cross-sectional study randomly enrolled cancer patients who were newly admitted to the medical oncology department of cancer institute of...

mycophenolate mofetil (mmf) as an immunosuppressive agent is used to prevent graft rejection. one of the adverse effects of long time administration of mmf is the gastrointestinal disorder. this study aimed to investigate the gastroprotective effect of silymarin (smn) on mmf-induced gastrointestinal (gi) disorders. twenty-four adult female wistar rats were assigned into three groups including t...

conclusions tg showed protective effect against ethanol induced gastric ulcer. this study confirmed traditional medicine claims of tg. objectives the aim of the present study was to determine the acute toxicity and protective effect of hydroalcoholic extract of tg (hetg) against ethanol induced gastric ulcer. materials and methods male wistar rats were divided into five groups (n = 7). hetg at ...

the aim of our work was to compare cytotoxic and membrane-damaging effects of o. majorana l. essential oil and linalool on hep g2 and to investigate their possible protective (antioxidant) effects against h2o2 induced membrane damage. the oils were investigated by gc and gc-ms and antioxidant activity was evaluated by dpph and -carotene–linoleic acid assays. assessment of cell viability was ma...

introduction: gp63 is a major surface protease of leishmania promastigotes that plays an important role in its virulance. as gp63 on its own can not develop an effective protection against leishmaniasis, the goal of this study was to evaluate the protective effect of gp63 conjugated with tetanus toxoid (tt) and vitamin d3 in susceptible balb/c mice against cutaneous leishmaniasis. methods: this...

background and purpose: many workers are exposed to workplace hazards. many occupational diseases are preventable by personal protective devices (ppds). though many workers do not use ppds or their protection by ppds is not sufficient. this study was designed to assess the quality of ppds usage among industrial workers. materials and methods: in a cross-sectional study, 648 workers from four ma...