Nobiletin is considered a phyto-flavonoid extracted from citrus peel and shown to several pharmacological roles such as anti-inflammatory, anti-tumor neuroprotective properties. In this study, we investigate the role of nobiletin combined docetaxel enhances apoptosis in colorectal cancer cell lines. Our results confirmed enhanced docetaxel-induced reactive oxygen species generation human carcin...

Background: The purpose of this study is to evaluate effects of Teucrium polium (TP) leaf extracts on adenosine monophosphate activated protein kinase (AMPK) level in isolated pancreases. Materials and Methods: In this experimental study, two groups of rats were used as a control group, and diabetic group. In the end of experimental period the animals were sacrificed then pancreas were removed...

Although ginsenoside Rg3 has been shown to exert anticancer effects on a variety of malignancies, the and molecular mechanisms oesophageal cancer remain unclear. Therefore, these factors must be explored. Here, we analyzed effect cell proliferation migration, as well its apoptosis. Furthermore, detected downstream pathways that could act on. The results showed significantly inhibited migration ...