BACKGROUND Endothelial dysfunction may be involved in the pathophysiology of cardiac abnormalities in patients with diabetes mellitus (DM). A correlation between endothelial dysfunction and diastolic dysfunction in patients with type 1 DM has been demonstrated, but this relationship has not been well investigated in type 2 DM. OBJECTIVE Compare groups of patients with type 2 DM and hypertensi...

OBJECTIVE To compare magnetic resonance imaging-derived right ventricular (RV) dimensions and function between men with type 2 diabetes and healthy subjects, and to relate these parameters to left ventricular (LV) dimensions and function. RESEARCH DESIGN AND METHODS RV and LV volumes and functions were assessed in 78 men with uncomplicated type 2 diabetes and 28 healthy men within the same ra...

Since the outbreak of SARS-CoV-2 pandemic in 2020, many governments have been imposing confinement and physical distancing measures. No data exist on effects lockdowns health status patients affected by chronic pathologies, specifically those with Chronic Obstructive Pulmonary Disease (COPD). Our study aims to establish variations across psychological cognitive profile during isolation period I...

It has been shown by cardiac catheterization that an increased resistance to blood flow through the lungs occurs in four main conditions: (1) congenital heart disease with potential shunt, (2) mitral valve disease or left ventricular failure, (3) chronic lung disease, and (4) primary and thromboembolic pulmonary hypertension. Although the burden of an increased pulmonary vascular resistance fal...

conclusions ipah is associated with subclinical hypothyroidism and low patient functional capacity, and is more common in rv failure. results in this research, 84.8% of the participants were women. the mean pap was 51.6 mmhg (31-87) and mean thyroid stimulating hormone (tsh) level was 4.2 miu/ml (0.7 - 10). subclinical hypothyroidism was detected in 26 patients (49.1%). there were significant c...

BACKGROUND Fentanyl is widely used off-label in NICU. Our aim was to investigate its cerebral, cardiovascular and pulmonary effects as well as pharmacokinetics in an experimental model for neonates. METHODS Fentanyl (5 µg/kg bolus immediately followed by a 90 minute infusion of 3 µg/kg/h) was administered to six mechanically ventilated newborn piglets. Cardiovascular, ventilation, pulmonary a...