Although insecticides play a crucial role in malaria control programs, this strategy is threatened by the development of resistance in the vectors to commonly used public health insecticides. Due to their known efficacy and lower toxicity to humans and non-target organisms, pyrethroids have been used in many vector control projects. In West Africa, pyrethroid resistance in the major malaria vec...

The cytochrome P450-dependent monooxygenases (P450s) are an important enzymatic system that metabolizes xenobiotics (e.g., pesticides), as well as endogenous compounds (e.g., hormones). P450-mediated metabolism can result in detoxification of insecticides such as pyrethroids, or can be involved in the bioactivation and detoxification of insecticides such as organophosphates. We isolated (from t...

Resistance to pyrethroids (the ingredients in bed net insecticides) in the major malaria vector Anopheles funestus is threatening recent gains in the fight against malaria. Here, we established the role of an over-expressed P450, A. funestus CYP6AA1 in insecticides resistance. Transcription profiling of CYP6AA1 across Africa using microarray and quantitative reverse transcription polymerase cha...

Abstract Background Pyrethroids have been widely used in the United States and worldwide. Few studies examined effect of pyrethroids exposure on sleep problems among adolescents. Objectives This study investigated associations between male female Methods The data were from National Health Nutrition Examination Survey 2007–2014. In this study, 3-Phenoxybenzoic Acid (3-PBA) was as a validated bio...

Honeybees and wild bees are among the most important pollinators of both cultivated landscapes. In recent years, however, a significant decline in these has been recorded. This decrease can have many causes including heavy use biocidal plant protection products agriculture. The frequent residues bee originate from fungicides, while neonicotinoids and, to lesser extent, pyrethroids popular insec...

Allethrin, present in mosquito coil is a pyrethroid pesticide. Pyrethroids are used as insecticides worldwide. Self poisoning with mosquito coil is very rare. We describe a case of attempted suicide by consumption of mosquito coil. Patient recovered without any sequel.