Background: This study was conducted to determine the effects of n-3 PUFAs supplementation on plasma homocysteine (Hcy) level, lipid profile and insulin resistance in patients with type 2 diabetes (T2D). Methods: This study is a double-blind controlled trial involving 70 patients with T2D selected from Yazd Diabetes Research Center in 2013. Patients were randomly assigned to receive either 2 g/...

Background: Acinetobacter baumannii is a highly virulent bacterium. It causes opportunistic and nosocomial infections and is a threat to healthcare settings. It has also developed multidrug resistance (MDR) capacity. The nosocomial bacteria and antibiotic resistance are primordial and a significant public health concern. These bacteria and their threat can be prevented by reducing infected food...

Background: Type II Diabetes mellitus (T2DM) is a multifactorial disease and a leading cause of premature deaths. Inflammatory cytokines are reported that they have potential to enhance insulin resistance and hence T2DM. Assessment of immunological profile in T2DM patients of Kashmir valley is unclear. So, detection of cytokines is relevant to determine the extent and direction of immune respon...

PURPOSE Resistance to antiangiogenic therapy is an important clinical problem. We examined whether resistance occurs at least in part via reversible, physiologic changes in the tumor, or results solely from stable genetic changes in resistant tumor cells. EXPERIMENTAL DESIGN Mice bearing two human RCC xenografts were treated with sorafenib until they acquired resistance. Resistant 786-O cells...

Introduction: Metabolic syndrome (MetS) and impaired lung functions have been associated with an increased risk for coronary heart disease. The aim of this study was to investigate the pulmonary functions in patients with MetS. Methods: This cross-sectional study included 200 subjects with MetS in the study group and 100 subjects without MetS in the control group. Participants were examined...

Obesity and insulin resistance are both associated with an atherogenic lipoprotein profile. We examined the effect of insulin sensitivity and central adiposity on lipoproteins in 196 individuals (75 men and 121 women) with an average age of 52.7 years. Subjects were subdivided into three groups based on BMI and their insulin sensitivity index (S(I)): lean insulin sensitive (n = 65), lean insuli...

INTRODUCTION AND OBJECTIVES To analyze the association between sitting time and biomarkers of insulin resistance and inflammation in a sample of healthy male workers. METHODS Cross-sectional study carried out in a sample of 929 volunteers belonging to the Aragon Workers' Health Study cohort. Sociodemographic, anthropometric, pharmacological and laboratory data were collected: lipids-total cho...

The aim of this study was to characterize 49 Salmonella Enteritidis (SE) isolates from different sources (poultry, human, cow, poultry house environment) in Iran with respect to drug resistance, plasmid profile, and random amplified polymorphic DNA (RAPD) analysis. Antimicrobial susceptibility test to 29 agents found 33 resistance patterns among the isolates. No resistance was observed to danof...