The first successful treatment of growth hormone (GH) deficient children with GH extracted from human pituitary was introduced during late 1950's.  The subsequent availability and use of recombinant GH (rhGH) for different clinical conditions raised the question of whether this new therapeutic modality increases the risk of certain conditions such as leukemia or malignancy.  Herein, we report o...

Purpose: To estimate interobserver agreement with regard to describing adnexalmasses using the InternationalOvarian Tumor Analysis (IOTA) terminology and the risk of malignancy calculated using IOTA logistic regression models LR1 and LR2, and to elucidate what explained the largest interobserver differences in calculated risk of malignancy. Experimental Design: One hundred and seventeen women w...

There are many studies which demonstrate a higher risk for malignancy in patients with rheumatic diseases. There have been a number of possible explanations for the differences in the risk of certain malignancies in patients with rheumatic disease, compared with general population, but a clear mechanism is difficult to identify.Rheumatoid syndromes may be associated with malignancy as paraneopl...

Abacus-based mental calculation (AMC) is a unique strategy for arithmetic that is based on the mental abacus. AMC experts can solve calculation problems with extraordinarily fast speed and high accuracy. Previous studies have demonstrated that abacus experts showed superior performance and special neural correlates during numerical tasks. However, most of those studies focused on the perception...

editorial The impact of treatment on the risk of second malignancy after Hodgkin's disease In the last several decades, there has been a steady improvement in the cure rate of patients diagnosed with Hodgkin's disease as more effective treatment and more accurate staging techniques become available [1]. With the growing number of patients surviving Hodgkin's disease, various delayed complicatio...

the first successful treatment of growth hormone (gh) deficient children with gh extracted from human pituitary was introduced during late 1950's.  the subsequent availability and use of recombinant gh (rhgh) for different clinical conditions raised the question of whether this new therapeutic modality increases the risk of certain conditions such as leukemia or malignancy.  herein, we report o...

Patients with Type 1 diabetes mellitus have a high prevalence of coeliac disease, symptoms of which are often mild, atypical, or absent. Untreated coeliac disease is associated with an increased risk of malignancy, particularly of lymphoma. Therefore, we report a 9-year-old girl with Coeliac disease, diabetes type 1 and Selective IgA deficiency. A 9-year-old female patient presented in august 2...

Liver transplant recipients have an increased risk of malignancy. Smoking is related to some of the most frequent causes of posttransplant malignancy. The incidence and risk factors for the development of neoplasia related to smoking (head and neck, lung, esophageal, and kidney and urinary tract carcinomas) were studied in 339 liver transplant recipients. Risk factors for the development of smo...