In 1988, the World Health Assembly resolved to eradicate poliomyelitis by the year 2000. Although substantial progress was achieved by 2000, global polio eradication proved elusive. In India, the goal was accomplished in 2011, and the entire South-East Asia Region was certified as polio-free in 2014. The year 2016 marks the lowest wild poliovirus type 1 case count ever, the lowest number of pol...

E356 CMAJ, April 19, 2011, 183(7) © 2011 Canadian Medical Association or its licensors Fifty years ago a team of doctors and nurses from the Nova Scotia Department of Health and Dalhousie University conducted what became known as the Wedgeport Polio Trial in which the oral trivalent Sabin vaccine was administered to an entire community in Southwest Nova Scotia. The results of the trial were pub...

1 Department of Microbiology, Immunology, and Tropical Medicine, The George Washington University and Sabin Vaccine Institute, Washington, D.C., United States of America, 2 Liverpool School of Tropical Medicine, Liverpool, United Kingdom, 3 Schistosomiasis Control Initiative, Imperial College London, United Kingdom, 4 Department of Neglected Tropical Diseases, World Health Organization, Geneva,...

Authors: Caroline Sabin ([email protected]) Peter Reiss ([email protected]) Lene Ryom ([email protected]) Andrew Phillips ([email protected]) Rainer Weber ([email protected]) Matthew Law ([email protected]) Eric Fontas ([email protected]) Amanda Mocroft ([email protected]) Stephane de Wit ([email protected]) Colette Smith ([email protected]) Francois...

When stationary cultures of human diploid cells in conventional Roux bottles were replaced by the development of cells in roller bottles, the yield of poliovirus, Sabin strains type 1 and 2, showed an increase of 0.5 to 1 log10. No significant difference was noticed in the yield of these viruses cultured in WI-38 and MRC-5 human diploid cells.

1 National School of Tropical Medicine and Department of Pediatrics and Molecular Virology & Microbiology at Baylor College of Medicine, Houston, Texas, United States of America, 2 Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development, Houston, Texas, United States of America, 3 American Society of Tropical Medicine and Hygiene, Deerfield, Illinois, United States ...

1 Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development, Department of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine, Baylor College of Medicine, Houston, Texas, United States of America, 2 Department of Biology, Baylor University, Waco, Texas, United States of America, 3 James A. Baker III Institute for Public Policy, Ri...

1 Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development, Houston, Texas, United States of America, 2 National School of Tropical Medicine, Department of Pediatrics and Molecular Virology & Microbiology, Baylor College of Medicine, Houston, Texas, United States of America, 3 James A. Baker III Institute for Public Policy, Rice University, Houston, Texas, United Sta...

A variant of the classical C Powell-Sabin-12 macro-element is defined that has the same approximation power, but has fewer degrees of freedom and only requires vertex data. The same idea is then applied to a related C trivariate macro-element. §

1 Departments of Pediatrics and Molecular Virology and Microbiology, National School of Tropical Medicine at Baylor College of Medicine, Houston, Texas, United States of America, 2 Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development, Houston, Texas, United States of America, 3 James A. Baker III Institute for Public Policy, Rice University, Houston, Texas, Unite...