Wisata Pasar Sabin merupakan kawasan persawahan (sabin) milik warga desa Hanura. Karang taruna Hanura bergotong royong membuat lokasi wisata karena potensi yang cukup potensial. Dalam meningkatkan dibutuhkan pemasaran baik, salah satunya adalah digital marketing. Kegiatan pengabdian kepada masyarakat ini upaya peningkatan wawasan marketing bagi karang dengan pelaksanaan kegiatan pelatihan. pela...

UNLABELLED To assess the dynamics of genetic reversion of live poliovirus vaccine in humans, we studied molecular evolution in Sabin-like poliovirus isolates from Nigerian acute flaccid paralysis cases obtained from routine surveillance. We employed a novel modeling approach to infer substitution and recombination rates from whole-genome sequences and information about poliovirus infection dyna...

BACKGROUND & OBJECTIVES Polioviruses are the causative agent of paralytic poliomyelitis. Attenuated polioviruses (Sabin oral poliovirus vaccine strains) do not replicate efficiently in neurons as compared to the wild type polioviruses and therefore do not cause disease. This study was aimed to investigate the differential host immune response to wild type 1 poliovirus (wild PV) and Sabin attenu...

Powell-Sabin splines are C-continuous quadratic splines defined on an arbitrary triangulation. Their construction is based on a particular split of each triangle in the triangulation into six smaller triangles. In this article we give an overview of the properties of Powell-Sabin splines in the context of computer aided geometric design. These splines can be represented in a compact normalized ...

To identify determinants of attenuation in the poliovirus type 1 Sabin vaccine strain, a series of recombinant viruses were constructed by using infectious cDNA clones of the virulent type 1 poliovirus P1/Mahoney and the attenuated type 1 vaccine strain P1/Sabin. Intracerebral inoculation of these viruses into transgenic mice which express the human receptor for poliovirus identified regions of...

Attenuated strains of the Sabin oral poliovirus vaccine replicate in the human gut and in rare cases cause vaccine-associated paralytic poliomyelitis (VAPP). Reversion of vaccine strains toward a pathogenic phenotype is probably one of the main causes of VAPP, a disease most frequently associated with type 3 and type 2 strains and more rarely with the type 1 (Sabin 1) strain. To identify the de...

The Sabin I poliovirus live, attenuated vaccine strain encodes for four amino acid changes (i.e., D53N, Y73H, K250E, and T362I) in the RNA-dependent RNA polymerase (RdRp). We have previously shown that the T362I substitution leads to a lower fidelity RdRp, and viruses encoding this variant are attenuated in a mouse model of poliovirus. Given these results, it was surprising that the nucleotide ...

1Department of Pathology, MD Anderson Cancer Institute, 1515 Holcombe Boulevard, Houston, TX 77030, USA 2Department of Pathology and Laboratory Medicine, College of Medicine, University of Cincinnati, MSB, 231 Albert Sabin Way, Cincinnati, OH 45221, USA 3Department of Pediatrics and Internal Medicine, College of Medicine, University of Cincinnati, MSB, 231 Albert Sabin Way, Cincinnati, OH 45221...

A Review of Public Citizens: The Attack on Big Government and the Remaking American Liberalism. By Paul Sabin.