Objectives Periodontal disease is an inflammatory condition of the tooth-supporting structures. Leptin is a hormone produced by the human body under different circumstances such as infection. It affects the production of cytokines, phagocytosis and the inflammation process. This study aimed to compare the salivary level of leptin in chronic periodontitis (CP) patients and healthy controls. Met...

Although periodontitis is a chronic inflammatory disease but some factors of acute inflammation phase are involved in this disease among which is the C-Reactive protein (CRP). To minimize its effects, anti-inflammatory drugs or non-pharmacological approaches such as oral hygiene is recommended. CRP can also be used for the prediction and early detection of periodontal disease. The aim of the pr...

BACKGROUND Upregulation of heparanase has been reported in an increasing number of human cancer tissues. However, the level of salivary heparanase and its clinical significance in patients with salivary gland tumors remain unclear. METHODS Salivary heparanase levels in patients with salivary gland tumors were detected using enzyme-linked immunosorbent assays (ELISAs) and the clinical signific...

BACKGROUND/AIMS Hyperphosphatemia is recognized as contributing to the increased risk of cardiac death in end-stage renal disease (ESRD) and hemodialysis (HD) patients. Currently available pharmacologic treatment for hyperphosphatemia is based on phosphate binders but, despite treatment, only half of the patients fall within the range for serum phosphorus of the K/DOQI guidelines. Therefore, th...

When salivary output is reduced chronically to a significant extent, there is a marked increase in dental caries. As the role of saliva in protection of the oral hard tissue is well recognized, there have long been efforts to enhance salivary function in conditions with associated secretory hypofunction. The rationale is that by stimulating salivary output, caries and other oral complications w...

objective(s): to review the findings of the patients with sjögren’s syndrome (ss) having technetium-99m-pertechnetate (99mtc-pertechnetate) and gallium-67 citrate (ga-67) salivary gland scintigraphy in the past eight years.methods: the patients with ss, who were referred to our department for salivary gland scintigraphy during january 2008-december 2015 were studied using both 99mtc-pertechneta...

introdouction: mucoepidermoid carcinoma (mec) is one of the most common salivary gland malignancies. the prevalence of salivary gland tumors varies in different geographic areas. in this report, we evaluated the prevalence of mec in iran and compared it with that previously reported in other countries. materials and methods: the files of oral pathology, shahid beheshti university of medical sci...

Saliva plays an essential role in maintaining oral health. Alterations in salivary function lead to compromise of oral tissues and functions and have a large impact on a patient’s quality of life. Reductions in salivary flow most commonly manifest as symptoms of oral dryness. This subjective complaint of dry mouth is termed xerostomia, whereas objective alterations in salivary performance, quan...

increased nitric oxide (no) formation is mechanistically linked to pathophysiology of the extrahepatic complications of cirrhosis. no is formed by either enzymatic or non-enzymatic pathways. enzymatic production is catalyzed by no synthase (nos) while entero-salivary circulation of nitrate and nitrite is linked to non-enzymatic formation of no under acidic ph in the stomach. there is no data on...