The long saphenous vein runs constantly in a deep plane of the hypodermis, lying directly above the muscular fascia (Figure 1). It is covered for its full length by a connective lamina that descends from the inguinal ligament to the ankle in the hypodermis of the medial thigh and leg. This lamina, which is formed by the interlacing of the hypodermal connective sheets, until now has been only pa...

OBJECTIVES The biological functions of transforming growth factor-β signaling that involves Smad proteins have not been previously investigated with respect to coronary artery bypass grafts. The aim of the present study was to observe the immunostaining of proteins that are related to this signaling pathway. METHODS Fifteen remnants of coronary artery bypass grafts, including nine saphenous v...

OBJECTIVES To compare the long-term results of stripping vs. haemodynamic correction (Ambulatory Conservative Haemodynamic Management of Varicose Veins, CHIVA) in the treatment of superficial venous incompetence resulting in chronic venous disease (CVD). DESIGN Randomised comparative trial. PATIENTS 150 patients affected by CVD, CEAP clinical class 2-6, were randomised to saphenous strippin...

Preoperative venous duplex scanning has revealed unexpected deep venous incompetence in patients with apparently only varicose veins. Acting on the hypothesis that the deep vein reflux was secondary to deep vein dilation caused by reflux volume, the following was done. Between July 1990 and April 1993, 29 limbs in 21 patients (16 females) were examined by color-flow duplex imaging to determine ...

This case study reports the diagnosis and treatment of a lower limb venous ulcer with abnormal underlying venous pathology. One male patient presented with bilateral varicose veins and a right lower limb ulcer. Upon investigation, full-leg duplex ultrasonography revealed total incompetence of the great saphenous vein in the left leg. In the right leg, duplex ultrasonography showed proximal inco...

Chronic vein insufficiency (CVI) is a disease which, when it develops, leads to varicose veins of the lower limbs. As approximately 25% to 50% of people suffer from it, it should be recognised as a public disease. The treatment of chronic vein insufficiency is based on a surgical approach. The aim of the operation is to remove (strip) the insufficient major saphenous vein (MSV), the main cause ...

The right gastroepiploic artery was successfully used for coronary artery bypass graft (CABG) in two patients whose saphenous veins were unavailable for grafting. One internal mammary artery was used in each patient. Because the gastroepiploic is an arterial pedicle, it is expected to have a good long-term patency rate and should be considered as an alternative conduit.

BACKGROUND Vascular endothelial growth factor (VEGF) mediates endothelial cell mitogenesis and enhances vascular permeability. The existence of single or multiple VEGF isoforms and receptors suggests that these proteins may have overlapping but distinct functions, which may be reflected in their cell expression and distribution. METHODS The localisation of VEGFs A-C and their receptors (VEGFR...

The present study reports on the selective effects on human platelets and canine saphenous veins of four stable difluorinated analogues and thromboxane A2 (TXA2), in which the characteristic 2,6-dioxa[3.1.1]bicycloheptane structure of TXA2 has been retained. The four compounds differ in their stereochemistry of the 5,6 double bond and/or the 15-hydroxyl group. Only 10,10-difluoro-TXA2 (compound...