Anatomic, histologic and ultrasound studies demonstrate two distinct types of longitudinal veins in the lower extremities. The great saphenous vein is deep to the saphenous fascia. Accessory saphenous veins are superficial to this layer, have thin walls with diminished muscle cells and elastic fibers. Vein characteristics may affect long-term graft patency. This study assesses the incidence of ...

introduction: endovenous laser therapy (evlt) for greater saphenous vein (gsv) insufficiency is a newly established method of treatment only recently made availablein iran. the present study seeks to describe the results of the first 20 patients treated with evlt at shohada-e tajrish medical center, tehran, iran. methods: 20 patients (16 male, 4 female) with the mean age of 38.9 and an average ...

Little is known regarding specific biologic and pharmacologic differences between human internal mammary arteries and saphenous veins. To better define the role of alpha-adrenoceptor-mediated vasoconstriction in human internal mammary arteries and saphenous veins, we obtained fresh specimens of both vessels from 32 patients undergoing coronary artery bypass surgery. Dose-response curves were ge...

Original Article Lower limb veins are most prone for venous disorders. Complete knowledge of the variations of great saphenous vein is of immense importance in assessment of clinical conditions like varicose veins, deep vein thrombosis and venous ulcer. Duplication of long saphenous vein is one of the potential reasons behind recurrence of varicosity after successful surgery. The present study ...

OBJECTIVE To investigate the possible role of apoptosis on brief distensions of human saphenous veins at different pressures. METHODS Fresh isolated grafts of human saphenous vein were assigned as control or distended (D) for fifteen seconds at 100, 200 and 300 mmHg. The degree of apoptotic caspases 3, 8, 9 and anti-apoptotic protein Bcl-2 expression were assessed by immunohistochemistry. R...

In the treatment of Chronic Venous Insufficiency (CVI) High Ligation (HL) and stripping saphenous varicose veins,

Varicose veins are a common condition attecting approximately 10 million patients in Japan. The main cause of varicose veins is reflux of the saphenous vein, and conventional treatment for several decades was stripping the affected saphenous vein and phlebectomy. Endovenous laser treatment (EVLT) is a less-invasive treatment method in which the saphenous vein is ablated with a laser under local...

Saphenous veins used as arterial grafts are exposed to arterial levels of oxygen partial pressure (pO2), which are much greater than what they experience in their native environment. The object of this study is to determine the impact of exposing human saphenous veins to arterial pO2. Saphenous veins and left internal mammary arteries from consenting patients undergoing coronary artery bypass g...

BACKGROUND The aim of this study was to evaluate the midterm clinical outcomes after modified high ligation and segmental stripping of small saphenous vein (SSV) varicosities. METHODS Between January 2010 and March 2013, 62 patients (69 legs) with isolated primary small saphenous varicose veins were enrolled in this study. The outcomes measured were reflux in the remaining distal SSV, the rec...

OBJECTIVE More than 50% of aortocoronary saphenous vein grafts are occluded 10 years after surgery. Intimal hyperplasia is an initial, critical step in the progression toward occlusion. To date, no clinically relevant large animal models of aortocoronary saphenous vein graft intimal hyperplasia have been fully characterized. Gene therapy holds promise as a novel treatment for aortocoronary saph...